Impact of physical function on indeterminable anaerobic threshold in patients with heart failure
| Title: | Impact of physical function on indeterminable anaerobic threshold in patients with heart failure |
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| Authors: | Sayano Ueda, Yuji Kono, Ryo Yamada, Tomoya Ishiguro, Masataka Yoshinaga, Satoshi Okumura, Wakaya Fujiwara, Mutsuharu Hayashi, Yoichiro Aoyagi, Eiichi Saitoh, Yohei Otaka, Hideo Izawa |
| Source: | Fujita Medical Journal, Vol 7, Iss 2, Pp 65-69 (2021) |
| Publisher Information: | Fujita Medical Society, 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Medicine (General) |
| Subject Terms: | anaerobic threshold, cardiopulmonary exercise testing, cardiac rehabilitation, exercise tolerance, heart failure, Medicine (General), R5-920 |
| More Details: | Background: Anaerobic threshold (AT) during cardiopulmonary exercise testing (CPET) is not always determinable in patients with heart failure (HF). However, little is known about the clinical features of patients with HF who have indeterminable AT. Therefore, the present study aimed to clarify the clinical features of such patients. Methods: A total of 70 patients with HF (58 males; age: 68±12 years) who underwent CPET during hospitalization were divided into two groups: determinable AT (n=50) and indeterminable AT (n=20). Physical function, echocardiographic results, and laboratory findings were subsequently determined. Results: Univariate analyses showed that the indeterminable AT group had significantly higher age and left ventricular ejection fraction, and significantly lower body mass index, calf circumference, handgrip strength, walking speed, serum hemoglobin, and serum albumin than the determinable AT group. Multiple logistic regression analysis identified handgrip strength and walking speed as independent predictive factors for indeterminable AT. Receiver-operating characteristic analyses revealed that handgrip strength of 21.2 kg and walking speed of 0.97 m/s were optimal cutoff values for differentiating patients who were likely to experience indeterminable AT. Conclusions: The present study identified handgrip strength and walking speed as powerful predictors for indeterminable AT with HF. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2189-7247 2189-7255 |
| Relation: | https://www.jstage.jst.go.jp/article/fmj/7/2/7_2020-015/_article/-char/en; https://doaj.org/toc/2189-7247; https://doaj.org/toc/2189-7255 |
| DOI: | 10.20407/fmj.2020-015 |
| Access URL: | https://doaj.org/article/39ab16ad1f6444b3b9514d1a72f1669b |
| Accession Number: | edsdoj.39ab16ad1f6444b3b9514d1a72f1669b |
| Database: | Directory of Open Access Journals |
| ISSN: | 21897247 21897255 |
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| DOI: | 10.20407/fmj.2020-015 |
| Published in: | Fujita Medical Journal |
| Language: | English |