Triple-negative breast cancer arising in a fibroadenoma in BRCA 1 mutated patient
Title: | Triple-negative breast cancer arising in a fibroadenoma in BRCA 1 mutated patient |
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Authors: | Nicole Brunetti, Irene Valente, Francesca Pitto, Massimo Calabrese |
Source: | Journal of Medical Ultrasound, Vol 31, Iss 1, Pp 63-65 (2023) |
Publisher Information: | Wolters Kluwer Medknow Publications, 2023. |
Publication Year: | 2023 |
Collection: | LCC:Medical technology |
Subject Terms: | brca, breast cancer on fibroadenoma, triple-negative breast cancer, Medical technology, R855-855.5 |
More Details: | We describe the case of a 35-year-old woman who comes to our institute with a palpable lump on her left breast. Clinically the mass was mobile, nontender and with no nipple discharge. Sonography revealed a circumscribed, oval-shaped, and hypoechoic mass, suggestive of a benign lesion. We performed an ultrasound-guided core needle biopsy that demonstrated multiple foci of high-grade (G3) ductal carcinoma in situ arising on fibroadenoma (FA). Subsequently, the patient had surgical excision of the mass with a final diagnosis of triple-negative breast cancer arising on FA. After diagnosis, the patient performs a genetic test that detects the BRCA 1 gene mutation. A review of the literature demonstrated only two cases of triple-negative breast cancer on FA. In this report, we describe another such case. |
Document Type: | article |
File Description: | electronic resource |
Language: | English |
ISSN: | 0929-6441 2212-1552 |
Relation: | http://www.jmuonline.org/article.asp?issn=0929-6441;year=2023;volume=31;issue=1;spage=63;epage=65;aulast=Brunetti; https://doaj.org/toc/0929-6441; https://doaj.org/toc/2212-1552 |
DOI: | 10.4103/jmu.jmu_83_21 |
Access URL: | https://doaj.org/article/3932c4bf60544a7fb1b10a7ce990dc4d |
Accession Number: | edsdoj.3932c4bf60544a7fb1b10a7ce990dc4d |
Database: | Directory of Open Access Journals |
ISSN: | 09296441 22121552 |
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DOI: | 10.4103/jmu.jmu_83_21 |
Published in: | Journal of Medical Ultrasound |
Language: | English |