Triple-negative breast cancer arising in a fibroadenoma in BRCA 1 mutated patient

Bibliographic Details
Title: Triple-negative breast cancer arising in a fibroadenoma in BRCA 1 mutated patient
Authors: Nicole Brunetti, Irene Valente, Francesca Pitto, Massimo Calabrese
Source: Journal of Medical Ultrasound, Vol 31, Iss 1, Pp 63-65 (2023)
Publisher Information: Wolters Kluwer Medknow Publications, 2023.
Publication Year: 2023
Collection: LCC:Medical technology
Subject Terms: brca, breast cancer on fibroadenoma, triple-negative breast cancer, Medical technology, R855-855.5
More Details: We describe the case of a 35-year-old woman who comes to our institute with a palpable lump on her left breast. Clinically the mass was mobile, nontender and with no nipple discharge. Sonography revealed a circumscribed, oval-shaped, and hypoechoic mass, suggestive of a benign lesion. We performed an ultrasound-guided core needle biopsy that demonstrated multiple foci of high-grade (G3) ductal carcinoma in situ arising on fibroadenoma (FA). Subsequently, the patient had surgical excision of the mass with a final diagnosis of triple-negative breast cancer arising on FA. After diagnosis, the patient performs a genetic test that detects the BRCA 1 gene mutation. A review of the literature demonstrated only two cases of triple-negative breast cancer on FA. In this report, we describe another such case.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 0929-6441
2212-1552
Relation: http://www.jmuonline.org/article.asp?issn=0929-6441;year=2023;volume=31;issue=1;spage=63;epage=65;aulast=Brunetti; https://doaj.org/toc/0929-6441; https://doaj.org/toc/2212-1552
DOI: 10.4103/jmu.jmu_83_21
Access URL: https://doaj.org/article/3932c4bf60544a7fb1b10a7ce990dc4d
Accession Number: edsdoj.3932c4bf60544a7fb1b10a7ce990dc4d
Database: Directory of Open Access Journals
More Details
ISSN:09296441
22121552
DOI:10.4103/jmu.jmu_83_21
Published in:Journal of Medical Ultrasound
Language:English