Academic Journal
Nanostarch based nanoencapsulation of Mucuna pruriens extract and its evaluation as anti-parkinsonian drug
| Title: | Nanostarch based nanoencapsulation of Mucuna pruriens extract and its evaluation as anti-parkinsonian drug |
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| Authors: | Ratnaningsih Eko Sardjono, Ramdhan Gunawan, Asep Kadarohman, Erdiwansyah, Rizalman Mamat, Melati Khairuddean |
| Source: | Case Studies in Chemical and Environmental Engineering, Vol 9, Iss , Pp 100562- (2024) |
| Publisher Information: | Elsevier, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Environmental engineering LCC:Chemical engineering |
| Subject Terms: | Anti–Parkinson, Mucuna pruriens, Nanoencapsulation, Nanostarch, Parkinson's disease, Environmental engineering, TA170-171, Chemical engineering, TP155-156 |
| More Details: | Parkinson's disease is a neurodegenerative disease caused by low dopamine levels in the brain. This study aims to obtain the optimum condition for M. pruriens extract nanoencapsulation in nano starch (NS-MPn) and nanostarch-maltodextrin (NS-MD-MPn), nanocapsules characteristics, and their potential as anti-Parkinsonian drug. The nanoencapsulation process was carried out by ultrasonic method. FTIR, SEM, and TEM carried out the characterization of NS-MPn and NS-MD-MPn nanocapsules. Encapsulation efficiency was evaluated by UV-Vis spectroscopy. SEM and TEM characterization NS-MPn and NS-MD-MPn nanocapsules have non-spherical surface morphology, spherical in shape 234.98 and 90.85 nm, respectively. NS-MPn have 21.35% encapsulation efficiency, meanwhile, NS-MD-MPn has 30.02%. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2666-0164 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2666016423002670; https://doaj.org/toc/2666-0164 |
| DOI: | 10.1016/j.cscee.2023.100562 |
| Access URL: | https://doaj.org/article/38939f357cbe491b996c8aca181593de |
| Accession Number: | edsdoj.38939f357cbe491b996c8aca181593de |
| Database: | Directory of Open Access Journals |
| ISSN: | 26660164 |
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| DOI: | 10.1016/j.cscee.2023.100562 |
| Published in: | Case Studies in Chemical and Environmental Engineering |
| Language: | English |