Bibliographic Details
| Title: |
Renin-angiotensin-aldosterone system inhibition decreased contrast-associated acute kidney injury in chronic kidney disease patients |
| Authors: |
Yi-Ting Chen, Chieh-Kai Chan, Wen-Yi Li, Tao-Min Huang, Tai-Shuan Lai, Vin-Cent Wu, Tzong-Shinn Chu |
| Source: |
Journal of the Formosan Medical Association, Vol 120, Iss 1, Pp 641-650 (2021) |
| Publisher Information: |
Elsevier, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Medicine (General) |
| Subject Terms: |
Renin-angiotensin-aldosterone system, Contrast nephropathy, Acute kidney disease, Chronic kidney disease, Medicine (General), R5-920 |
| More Details: |
Background/Purpose: Chronic kidney disease (CKD) is a risk factor for contrast associated acute kidney injury (CA-AKI). The risk of renin-angiotensin-aldosterone system inhibitor (RASi) use in patients with CKD before the administration of contrast is not clear. Methods: In this nested case–control study, 8668 patients received contrast computed tomography (CT) from 2013 to 2018 during index administration in a multicenter hospital cohort. The identification of AKI is based on the Kidney Disease: Improving Global Outcomes (KDIGO) serum creatinine criteria within 48 h after contrast medium used. Results: Finally, 986 patients (age, 63.36 ± 12.22; men, 72.92%) with CKD (estimated glomerular filtration rate (eGFR) = 35.0 ± 19.8 mL/min/1.73 m2) were eligible for analysis. After the index date, RASi users (n = 315) were less likely to develop CA-AKI (13.65% vs 30.4%, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
0929-6646 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S092966462030334X; https://doaj.org/toc/0929-6646 |
| DOI: |
10.1016/j.jfma.2020.07.022 |
| Access URL: |
https://doaj.org/article/3854db1e9d254a2abf5051e28343b497 |
| Accession Number: |
edsdoj.3854db1e9d254a2abf5051e28343b497 |
| Database: |
Directory of Open Access Journals |
