Bibliographic Details
Title: |
Molecular Targets of Active Anticancer Compounds Derived from Marine Sources |
Authors: |
Xiaoping Song, Ying Xiong, Xin Qi, Wei Tang, Jiajia Dai, Qianqun Gu, Jing Li |
Source: |
Marine Drugs, Vol 16, Iss 5, p 175 (2018) |
Publisher Information: |
MDPI AG, 2018. |
Publication Year: |
2018 |
Collection: |
LCC:Biology (General) |
Subject Terms: |
marine sources, anticancer compounds, molecular targets, Biology (General), QH301-705.5 |
More Details: |
Over the past decades, a number of novel compounds, which are produced in the marine environment, have been found to exhibit the anticancer effects. This review focuses on molecular targets of marine-derived anticancer candidates in clinical and preclinical studies. They are kinases, transcription factors, histone deacetylase, the ubiquitin-proteasome system, and so on. Specific emphasis of this review paper is to provide information on the optimization of new target compounds for future research and development of anticancer drugs, based on the identification of structures of these target molecules and parallel compounds. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
1660-3397 |
Relation: |
http://www.mdpi.com/1660-3397/16/5/175; https://doaj.org/toc/1660-3397 |
DOI: |
10.3390/md16050175 |
Access URL: |
https://doaj.org/article/384878ee9a5b4c53a3449f2663e281d4 |
Accession Number: |
edsdoj.384878ee9a5b4c53a3449f2663e281d4 |
Database: |
Directory of Open Access Journals |