Fungal Infection of the Sinus and Anterior Skull Base
| Title: | Fungal Infection of the Sinus and Anterior Skull Base |
|---|---|
| Authors: | Morteza Javadi, Shabahang Mohammadi |
| Source: | Medical Journal of The Islamic Republic of Iran, Vol 22, Iss 3, Pp 137-140 (2008) |
| Publisher Information: | Iran University of Medical Sciences, 2008. |
| Publication Year: | 2008 |
| Collection: | LCC:Medicine (General) |
| Subject Terms: | Sinusitis, Rhinocerebral, Nasal, Orbital, Anterior Sull Base, Medicine (General), R5-920 |
| More Details: | Abstract Background: Invasive fungal infection is an opportunistic infection caused commonly by mucoraccae and aspergillus. It mostly occurs in patients with underlying disease. Since it has a high mortality and morbidity rate, considering a treatment strategy seems necessary. Objective: Since there has not been a clear protocol for treating these patients, we decided to establish a protocol for fungal infection of sinus and anterior skull base management. Methods: This retrospective and descriptive case study series included 30 patients. After confirming the pathogen, the authors came to a proper protocol for treatment which is mentioned later. Results: The site involvement included nose and orbital cavity (53.3%), anterior skull base and brain in conjunction with sinonasal (36.6%) and simple nasal cavity involvement (10%). 86.6% of the patients had underlying diseases. 56.6% of patients had diabetes as a single underlying disease, while 13.3% had both diabetes and renal failure in combination. Acute lymphocytic leukemia was present in 6.6%, renal failure in 3.3%, lupus in 3.3% and chronic lymphocytic leukemia in 3.3% of patients. Mortality rate was 40%. We categorized the patients into 3 groups: only sinonasal, sinonasal and orbit, and associated anterior skull base and brain involvement. Conclusion: Early diagnosis is an important factor in improving survival. Anterior skull base and brain involvement has a very poor prognosis. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1016-1430 2251-6840 |
| Relation: | http://mjiri.tums.ac.ir/browse.php?a_code=A-10-1-5&slc_lang=en&sid=1; https://doaj.org/toc/1016-1430; https://doaj.org/toc/2251-6840 |
| Access URL: | https://doaj.org/article/379ceccb735646ca87d3a10834b9d781 |
| Accession Number: | edsdoj.379ceccb735646ca87d3a10834b9d781 |
| Database: | Directory of Open Access Journals |
| ISSN: | 10161430 22516840 |
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| Published in: | Medical Journal of The Islamic Republic of Iran |
| Language: | English |