Bibliographic Details
| Title: |
Preoperative red cell distribution width is associated with postoperative lymphovascular invasion in prostate cancer patients treated with radical prostatectomy: A retrospective study |
| Authors: |
Fangming Wang, Jing Liang, Feiya Yang, Fei Liu, Sujun Han, Nianzeng Xing |
| Source: |
Frontiers in Endocrinology, Vol 13 (2022) |
| Publisher Information: |
Frontiers Media S.A., 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
| Subject Terms: |
red blood cell distribution width, lymphovascular invasion, prostate cancer, radical prostatectomy, hematological parameters, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| More Details: |
PurposeTo investigate the relationship between baseline clinicopathological and laboratory variables especially hematological parameters and lymphovascular invasion (LVI) in patients who underwent radical prostatectomy (RP).MethodsWe retrospectively evaluated 348 prostate cancer (PCa) patients who underwent RP in our center between May 2018 and June 2021. We divided them into non-LVI and LVI groups based on LVI status, and compared clinicopathological characteristics between non-LVI and LVI groups. Clinicopathological parameters including age, body mass index (BMI), history of hypertension and diabetes mellitus, neoadjuvant hormonal therapy (NHT), pathological stage T (pT) and lymph node status (pN), ISUP (international society of urological pathology) grade, positive surgical margin (PSM) rate, and hematological parameters containing prostate-specific antigen (PSA), whole blood parameters and inflammatory indexes were collected. The association between the clinicopathological parameters and the presence of LVI was identified by multivariate logistic regression analysis.ResultsThe pathological results of the RP specimen consisted of 53 (15.2%) patients with LVI and 295 (84.8%) cases without LVI. The level of PSA, percentages of advanced pT and grade, pN1, and PSM were significantly higher in the LVI group when compared with the non-LVI counterpart (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1664-2392 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fendo.2022.1020655/full; https://doaj.org/toc/1664-2392 |
| DOI: |
10.3389/fendo.2022.1020655 |
| Access URL: |
https://doaj.org/article/de36cb0b4be94f1b9ec9c308b076e2d1 |
| Accession Number: |
edsdoj.36cb0b4be94f1b9ec9c308b076e2d1 |
| Database: |
Directory of Open Access Journals |
