Insights into Visual Outcomes and Determinants in Pituitary Adenoma Surgery: A 5-Year Retrospective Cohort Study
| Title: | Insights into Visual Outcomes and Determinants in Pituitary Adenoma Surgery: A 5-Year Retrospective Cohort Study |
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| Authors: | Kemchoknatee P, Singhakul C, Arjkongharn N, Vongsa N, Tangon D, Srisombut T |
| Source: | Clinical Ophthalmology, Vol Volume 18, Pp 1779-1788 (2024) |
| Publisher Information: | Dove Medical Press, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Ophthalmology |
| Subject Terms: | pituitary adenoma, visual outcome, transsphenoidal surgery, transcranial surgery, thai, Ophthalmology, RE1-994 |
| More Details: | Parinee Kemchoknatee,1,2,* Chotika Singhakul,1 Niracha Arjkongharn,1 Nattaporn Vongsa,1 Duanghathai Tangon,2 Thansit Srisombut3,* 1Division of Neuro-Ophthalmology, Department of Ophthalmology, Rajavithi Hospital, Bangkok, Thailand; 2Faculty of Medicine, Rangsit University, Rajavithi Hospital, Bangkok, Thailand; 3Department of Surgery, Sawanpracharak Hospital, Nakhon Sawan, Thailand*These authors contributed equally to this workCorrespondence: Parinee Kemchoknatee, Division of Neuro-ophthalmology, Department of Ophthalmology, Rajavithi Hospital, Phayathai, Ratchathewi, Bangkok, Thailand, Email parinee.eye52@gmail.comPurpose: To investigate the long-term visual outcome and their determinants after an operation in Thai pituitary adenoma (PA).Patients and Methods: A retrospective cohort study was conducted on PA patients who underwent surgery at Rajavithi Hospital. Baseline characteristics and visual parameters, including visual acuity (VA) and visual field (VF), were analyzed in relation to the visual prognosis outcome. The outcome was defined as VA improvement at 1-year postoperatively. Visual parameters were measured at each follow-up visit and compared. Factors for improved visual prognosis were evaluated using logistic regression analysis.Results: A total cohort of 87 patients (64.37% female), 62.07% showed improvement in visual outcome. Most improvement occurred immediately after surgery, evident at the 1-month visit. The mean follow-up time was 47.45 months (± 28.49 SD), mean difference in VA improvement at 1-year was − 0.56 logMAR (95% CI − 0.73, − 0.47). In multivariable logistic regression model, prolonged onset duration was associated with a reduced odds of improved visual outcome, with an odds ratio (OR) of 0.946 (95% CI 0.899– 0.996, p = 0.034). Baseline characteristics, tumor volume, Hardy and Knops classification, and surgical approaches were not identified as significant predictors.Conclusion: Both TSS and transcranial approaches are effective for pituitary adenoma. A prompt operation is recommended for patients with prolonged onset duration, with thorough discussion on poor postoperative visual outcomes.Keywords: pituitary adenoma, visual outcome, transsphenoidal surgery, transcranial surgery, Thai |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1177-5483 17577748 |
| Relation: | https://www.dovepress.com/insights-into-visual-outcomes-and-determinants-in-pituitary-adenoma-su-peer-reviewed-fulltext-article-OPTH; https://doaj.org/toc/1177-5483 |
| Access URL: | https://doaj.org/article/a35e3b17577748389f1563f26694bba6 |
| Accession Number: | edsdoj.35e3b17577748389f1563f26694bba6 |
| Database: | Directory of Open Access Journals |
| ISSN: | 11775483 17577748 |
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| Published in: | Clinical Ophthalmology |
| Language: | English |