Bibliographic Details
| Title: |
Associations between parental psychopathology and youth functional emotion regulation brain networks |
| Authors: |
Valerie Karl, Dani Beck, Espen Eilertsen, Carmen Morawetz, Thea Wiker, Eira R. Aksnes, Linn.B. Norbom, Lia Ferschmann, Niamh MacSweeney, Irene Voldsbekk, Ole A. Andreassen, Lars T. Westlye, Dylan G. Gee, Haakon Engen, Christian K. Tamnes |
| Source: |
Developmental Cognitive Neuroscience, Vol 70, Iss , Pp 101476- (2024) |
| Publisher Information: |
Elsevier, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Neurophysiology and neuropsychology |
| Subject Terms: |
Parental psychopathology, Youth, Emotion regulation networks, Functional connectivity, Youth mental health, ABCD, Neurophysiology and neuropsychology, QP351-495 |
| More Details: |
Parental mental health is associated with children’s emotion regulation (ER) and risk for psychopathology. The relationship between parental psychopathology and children’s functional ER networks and whether connectivity patterns mediate the relationship between parent and youth psychopathology remains unexplored. Using resting-state functional magnetic resonance imaging data from the Adolescent Brain Cognitive Development Study (N = 4202, mean age = 10.0) and a multilevel approach, we analyzed the relationship between self-reported parental psychopathology and their offsprings’ connectivity of four ER networks, as well as associations with self-reported youth psychopathology at a 3-year follow-up. Parental internalizing and total problems were associated with 1) higher connectivity between a subcortical-cortical integrative and ventrolateral prefrontal cortical (PFC) network, 2) lower connectivity between dorsolateral and ventrolateral PFC networks involved in cognitive aspects of ER, and 3) lower connectivity within a subcortical ER network (β = −0.05–0.04). Parental externalizing and total problems were associated with lower connectivity within the integrative network (βext = −0.05; βtot = −0.04). Mediation analyses yielded direct effects of parental to youth psychopathology, but no mediation effect of ER network connectivity. Overall, our results show that ER network connectivity in youth is related to parental psychopathology, yet do not explain intergenerational transmission of psychopathology. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1878-9293 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1878929324001373; https://doaj.org/toc/1878-9293 |
| DOI: |
10.1016/j.dcn.2024.101476 |
| Access URL: |
https://doaj.org/article/35d5a8ad0a8c4a6cb26a4244adc61092 |
| Accession Number: |
edsdoj.35d5a8ad0a8c4a6cb26a4244adc61092 |
| Database: |
Directory of Open Access Journals |
