Bibliographic Details
| Title: |
Polisitemi Veralı Hastalarda Dinamik Thiol/Disulfit Dengesi ve İskemi Modifiye Albumin Düzeyleri |
| Authors: |
Özcan Erel, Hakan Basir, Mustafa Ilgan, Eyüp Naci Tiftik, Mahmut Bakır Koyuncu, Mehmet Ali Uçar, Aydan Akdeniz, Anıl Tombak, Salim Neşelioğlu |
| Source: |
Düzce Tıp Fakültesi Dergisi, Vol 23, Iss 2, Pp 137-141 (2021) |
| Publisher Information: |
Duzce University, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Medicine
LCC:Medicine (General) |
| Subject Terms: |
disulfit, polistemi vera, oksidatif stres, tiyol, disulfide, polycythemia vera, oxidative stress, thiol, Medicine, Medicine (General), R5-920 |
| More Details: |
Aim: Polycythemia vera is a chronic myeloproliferative disease characterized by increased red cell mass and JAK2 mutation positivity. Transformation to myelofibrosis and acute leukemia is possible in patients with polycythemia vera. Oxidative stress causes DNA damage and might be a reason for malignant transformation. Thiol molecules can prevent the harmful effects of oxidative stress. Therefore, in this study, we aimed to analyze the state of thiol homeostasis in patients with polycythemia vera. Material and Methods: Thirty-one patients with polycythemia vera and 80 healthy volunteers were included in this study. Serum samples of the cases were stored until the end of the study. Native thiol, total thiol, disulfide, and ischemia modified albumin levels were determined. Results: The mean ischemia modified albumin (1.09±0.21 vs 0.67±0.08; p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1307-671X |
| Relation: |
https://dergipark.org.tr/tr/download/article-file/1614311; https://doaj.org/toc/1307-671X |
| DOI: |
10.18678/dtfd.890142 |
| Access URL: |
https://doaj.org/article/35b4e1f5780c4d1e96365e2e5cd73d67 |
| Accession Number: |
edsdoj.35b4e1f5780c4d1e96365e2e5cd73d67 |
| Database: |
Directory of Open Access Journals |
