Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

Bibliographic Details
Title: Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
Authors: Quentin R. V. Ferry, Radostina Lyutova, Tudor A. Fulga
Source: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Publisher Information: Nature Portfolio, 2017.
Publication Year: 2017
Collection: LCC:Science
Subject Terms: Science
More Details: Being able to regulate gene expression in a controllable manner is one of the promises of synthetic biology, and CRISPR-Cas9 is one of the tools being developed to achieve that goal. Here the authors develop an inducible CRISPR platform using an engineered guide RNA.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/ncomms14633
Access URL: https://doaj.org/article/c3599b79b8d04d34aa8e0a984e7a35c2
Accession Number: edsdoj.3599b79b8d04d34aa8e0a984e7a35c2
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/ncomms14633
Published in:Nature Communications
Language:English