Bibliographic Details
| Title: |
CiLiQuant: Quantification of RNA Junction Reads Based on Their Circular or Linear Transcript Origin |
| Authors: |
Annelien Morlion, Eva Hulstaert, Marieke Vromman, Jasper Anckaert, Celine Everaert, Jo Vandesompele, Pieter Mestdagh |
| Source: |
Frontiers in Bioinformatics, Vol 2 (2022) |
| Publisher Information: |
Frontiers Media S.A., 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Computer applications to medicine. Medical informatics |
| Subject Terms: |
RNA, circular, linear, splicing, bioinformatics, Computer applications to medicine. Medical informatics, R858-859.7 |
| More Details: |
Distinguishing circular RNA reads from reads derived from the linear host transcript is a challenging task because of sequence overlap. We developed a computational approach, CiLiQuant, that determines the relative circular and linear abundance of transcripts and gene loci using back-splice and unambiguous forward-splice junction reads generated by existing mapping and circular RNA discovery tools. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2673-7647 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fbinf.2022.834034/full; https://doaj.org/toc/2673-7647 |
| DOI: |
10.3389/fbinf.2022.834034 |
| Access URL: |
https://doaj.org/article/35276272e3f646908fd1b3e4a0342fa3 |
| Accession Number: |
edsdoj.35276272e3f646908fd1b3e4a0342fa3 |
| Database: |
Directory of Open Access Journals |
