Should the management of high grade cervical squamous intraepithelial lesion (HSIL) be different in HIV-positive women?

Bibliographic Details
Title: Should the management of high grade cervical squamous intraepithelial lesion (HSIL) be different in HIV-positive women?
Authors: Christine Gilles, Maude Velghe-lenelle, Yannick Manigart, Déborah Konopnicki, Serge Rozenberg
Source: AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-11 (2021)
Publisher Information: BMC, 2021.
Publication Year: 2021
Collection: LCC:Immunologic diseases. Allergy
Subject Terms: HIV, HSIL, Treatment failure, CIN, Immunologic diseases. Allergy, RC581-607
More Details: Abstract Background This study compares the management and outcome of high grade squamous intraepithelial lesions (HSIL) in HIV-positive and -negative women and identifies risk factors for treatment failure. Methods This retrospective, controlled study includes 146 HIV-positive women, matched for HSIL, age and year of diagnosis, with 146 HIV-negative women. Differences were analysed using parametric and non-parametric tests and Kaplan–Meier survival curves. A binary logistic regression was used to assess risk factors for treatment failure. Results Persistence of cervical disease was observed most frequently in HIV-positive women (42 versus 17%) (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1742-6405
Relation: https://doaj.org/toc/1742-6405
DOI: 10.1186/s12981-021-00371-x
Access URL: https://doaj.org/article/e34fe58fa39a4fc492f61435af24e23a
Accession Number: edsdoj.34fe58fa39a4fc492f61435af24e23a
Database: Directory of Open Access Journals
More Details
ISSN:17426405
DOI:10.1186/s12981-021-00371-x
Published in:AIDS Research and Therapy
Language:English