Bibliographic Details
| Title: |
Dysphagia, nutritional status, and quality of life in patients with head and neck cancer undergoing radiotherapy alone or combined with chemotherapy: an observational study |
| Authors: |
Marina de Castro Monteiro Franco Gomes, Pedro Maciel de Vasconcellos Ferreira, Ana Clara Speziali Menegazzi Almeida, Júlia Soares Cornélio, Thiago Jardim Arruda, Arnoldo Mafra, Marcelo Henrique Silva Nunes, Rafael Borges Salera, Raquel Fabiane Nogueira, Juliana Maria Braga Sclauser, Poliana Mendes de Andrade, Luciana Priscila Marçal, Ana Paula Drummond-Lage, Bruno Almeida Rezende |
| Source: |
BMC Cancer, Vol 25, Iss 1, Pp 1-11 (2025) |
| Publisher Information: |
BMC, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
Head and neck cancer, Radiotherapy, Chemotherapy, Dysphagia, Quality of life, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
Abstract Introduction Radiotherapy (RT) is the most common nonsurgical treatment for head and neck cancer (HNC) and may or may not be combined with chemotherapy (CT). Dysphagia, characterized by impaired swallowing function, is one of the most common side effects of RT, occurring during and after RT, and may persist long after treatment. Objective To compare the evolution of dysphagia, nutritional status, and quality of life (QoL) in the periods immediately before and after RT for HNC in individuals who received only RT or combined RT/CT. Methods Prospective longitudinal observational study performed in a hospital of the Brazilian public health system. The individuals were allocated into two groups: RG (n = 20), consisting of patients who received only RT for HNC, and RCG (n = 27), who received RT plus CT. The patients were evaluated before and after RT to identify and classify dysphagia (PARD protocol), anthropometric variables (BMI, triceps skinfold thickness, arm and calf circumferences, and manual dynamometry), and QoL (QLC-30 and H&N-35 questionnaires). Results The groups were homogeneous in demographic characteristics and tumor stage. RCG showed a higher proportion of worsening dysphagia severity (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2407 |
| Relation: |
https://doaj.org/toc/1471-2407 |
| DOI: |
10.1186/s12885-025-13695-y |
| Access URL: |
https://doaj.org/article/340706bb81f34150af8b8e0a343660ad |
| Accession Number: |
edsdoj.340706bb81f34150af8b8e0a343660ad |
| Database: |
Directory of Open Access Journals |
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