Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study

Bibliographic Details
Title: Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study
Authors: Jiajia Zhang, Jia Kang, Xueling Song, Shuo Yang, Yan Yang, Jie Qiao, Caihong Ma
Source: BMC Women's Health, Vol 24, Iss 1, Pp 1-7 (2024)
Publisher Information: BMC, 2024.
Publication Year: 2024
Collection: LCC:Gynecology and obstetrics
LCC:Public aspects of medicine
Subject Terms: Septate uterus, Septum incision, In vitro Fertilization, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270
More Details: Abstract Objective This retrospective study aimed to assess the impact of hysteroscopic septum incision on in vitro fertilization (IVF) outcomes among infertile women diagnosed with a complete septate uterus and no history of recurrent pregnancy loss. Methods The study was conducted at a tertiary reproductive center affiliated with a university hospital and involved 78 women with a complete septate uterus. Among them, 34 women underwent hysteroscopic septum incision, while 44 women opted for expectant management. The primary outcome measure was the live birth rate, while secondary outcomes included clinical pregnancy rate, preterm birth rate, miscarriage rate, and ongoing pregnancy rate. Results Women who underwent hysteroscopic septum incision demonstrated a comparable likelihood of achieving a live birth compared to those managed expectantly (25% vs. 25%, Relative Risk (RR): 1.000, 95% Confidence Interval (CI): 0.822 to 1.216). No preterm births occurred in either group. The clinical pregnancy rate, ongoing pregnancy rate, and miscarriage rate showed no significant differences between the surgical group and the expectant management group. Subgroup analyses based on the type of embryo transferred also revealed no significant differences in outcomes. Conclusions Hysteroscopic septum incision does not appear to yield improved IVF outcomes compared to expectant management in infertile women with a complete septate uterus and no history of recurrent pregnancy loss.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1472-6874
Relation: https://doaj.org/toc/1472-6874
DOI: 10.1186/s12905-024-03022-1
Access URL: https://doaj.org/article/336febec904d47788c6ec7c72f248221
Accession Number: edsdoj.336febec904d47788c6ec7c72f248221
Database: Directory of Open Access Journals
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More Details
ISSN:14726874
DOI:10.1186/s12905-024-03022-1
Published in:BMC Women's Health
Language:English