Bibliographic Details
| Title: |
Targeted Metabolomics to Assess Exposure to Environmental Chemicals of Concern in Japanese Quail at Two Life Stages |
| Authors: |
Elena Legrand, Niladri Basu, Markus Hecker, Doug Crump, Jianguo Xia, Bharat Chandramouli, Heather Butler, Jessica A. Head |
| Source: |
Metabolites, Vol 11, Iss 12, p 850 (2021) |
| Publisher Information: |
MDPI AG, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Microbiology |
| Subject Terms: |
environmental metabolomics, avian, early life stage, mass spectrometry, LC-MS, Microbiology, QR1-502 |
| More Details: |
This proof-of-concept study characterizes the Japanese quail (Coturnix japonica) hepatic metabolome following exposure to benzo[a]pyrene, chlorpyrifos, ethinylestradiol, fluoxetine hydrochloride, hexabromocyclododecane, lead(II)nitrate, seleno-L-methionine, and trenbolone in embryos and adults. The analysis revealed effects on lipid metabolism following exposure to several chemicals at both life stages. The most pronounced effects were observed in embryos exposed to 41.1 μg/g chlorpyrifos. This work highlighted challenges and the need for further avian metabolomics studies. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2218-1989 |
| Relation: |
https://www.mdpi.com/2218-1989/11/12/850; https://doaj.org/toc/2218-1989 |
| DOI: |
10.3390/metabo11120850 |
| Access URL: |
https://doaj.org/article/32b916d1db044f91a74d5491951e7c3a |
| Accession Number: |
edsdoj.32b916d1db044f91a74d5491951e7c3a |
| Database: |
Directory of Open Access Journals |
