Academic Journal
High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program
| Title: | High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program |
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| Authors: | David P. Labbé, Giorgia Zadra, Meng Yang, Jaime M. Reyes, Charles Y. Lin, Stefano Cacciatore, Ericka M. Ebot, Amanda L. Creech, Francesca Giunchi, Michelangelo Fiorentino, Habiba Elfandy, Sudeepa Syamala, Edward D. Karoly, Mohammed Alshalalfa, Nicholas Erho, Ashley Ross, Edward M. Schaeffer, Ewan A. Gibb, Mandeep Takhar, Robert B. Den, Jonathan Lehrer, R. Jeffrey Karnes, Stephen J. Freedland, Elai Davicioni, Daniel E. Spratt, Leigh Ellis, Jacob D. Jaffe, Anthony V. DʼAmico, Philip W. Kantoff, James E. Bradner, Lorelei A. Mucci, Jorge E. Chavarro, Massimo Loda, Myles Brown |
| Source: | Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
| Publisher Information: | Nature Portfolio, 2019. |
| Publication Year: | 2019 |
| Collection: | LCC:Science |
| Subject Terms: | Science |
| More Details: | Prostate cancer progression may be enhanced by a high-fat diet. Here the authors show that a diet high in saturated fats enhance the MYC-driven transcriptional program, a feature that independently predicts prostate cancer progression and death. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2041-1723 47838760 |
| Relation: | https://doaj.org/toc/2041-1723 |
| DOI: | 10.1038/s41467-019-12298-z |
| Access URL: | https://doaj.org/article/ad31beb7d54c47838760eb7ff3f13cf9 |
| Accession Number: | edsdoj.31beb7d54c47838760eb7ff3f13cf9 |
| Database: | Directory of Open Access Journals |
| ISSN: | 20411723 47838760 |
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| DOI: | 10.1038/s41467-019-12298-z |
| Published in: | Nature Communications |
| Language: | English |