Bibliographic Details
| Title: |
Analysis of Periprocedural X-ray Exposure in Transarterial Radioembolization with Glass or Resin Microspheres |
| Authors: |
Constantin Ehrengut, Johanna Vogt, Jakob Leonhardi, Emma Carabenciov, Felix Teske, Florian van Boemmel, Thomas Berg, Daniel Seehofer, Thomas Lincke, Osama Sabri, Holger Gößmann, Timm Denecke, Sebastian Ebel |
| Source: |
Diagnostics, Vol 13, Iss 24, p 3609 (2023) |
| Publisher Information: |
MDPI AG, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Medicine (General) |
| Subject Terms: |
Transarterial Radioembolization, radiation protection, Medicine (General), R5-920 |
| More Details: |
Background: Transarterial Radioembolization (TARE) is an effective treatment option for both primary and secondary liver malignancies. However, challenging anatomical conditions can lead to prolonged fluoroscopy times (FT), elevated doses of periprocedural X-radiation (DAP), and increased use of contrast agents (CAs). In this study, we examined the influence of our radiologists’ experience and the choice of microspheres on X-ray exposure and CA doses in TARE. Material and Methods: Datasets comprising 161 TARE and 164 preprocedural evaluation angiographies (TARE-EVA) were analyzed. Our study focused on assessing DAP, FT, and CA concerning both microsphere types, the radiologist’s experience, and whether the same radiologist performed both the TARE-EVA and the actual TARE. Results: In TARE, the use of resin microspheres resulted in significantly higher FT and CA compared to glass microspheres (14.3 ± 1.6 min vs. 10.6 ± 1.1 min and 43 ± 2.2 mL vs. 33.6 ± 2.1 mL, p < 0.05), with no notable differences in DAP (p = 0.13). Experienced radiologists demonstrated reduced FT/DAP, with a 19% decrease in DAP and 53% in FT during the evaluation angiography (p < 0.05) and a 49% reduction in DAP during the actual TARE (p < 0.05), with no statistical differences in FT. Performing TARE and TARE-EVA under the same radiologist led to a 43% reduction in DAP and a 25% decrease in FT (p < 0.05, respectively). Conclusions: To mitigate X-radiation exposure, it is advisable for radiologists to undergo thorough training, and, ideally, the same radiologist should conduct both the TARE and the TARE-EVA. While the use of glass spheres may decrease intraarterial CA, it does not significantly impact periprocedural X-ray exposure. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2075-4418 |
| Relation: |
https://www.mdpi.com/2075-4418/13/24/3609; https://doaj.org/toc/2075-4418 |
| DOI: |
10.3390/diagnostics13243609 |
| Access URL: |
https://doaj.org/article/3101c054b00c480d84aaca24da2a3680 |
| Accession Number: |
edsdoj.3101c054b00c480d84aaca24da2a3680 |
| Database: |
Directory of Open Access Journals |
