Bibliographic Details
Title: |
Reshaping Our Knowledge: Advancements in Understanding the Immune Response to Human Respiratory Syncytial Virus |
Authors: |
Federica Attaianese, Sara Guiducci, Sandra Trapani, Federica Barbati, Lorenzo Lodi, Giuseppe Indolfi, Chiara Azzari, Silvia Ricci |
Source: |
Pathogens, Vol 12, Iss 9, p 1118 (2023) |
Publisher Information: |
MDPI AG, 2023. |
Publication Year: |
2023 |
Collection: |
LCC:Medicine |
Subject Terms: |
immune response, RSV, syncytial respiratory virus, prevention strategy, Medicine |
More Details: |
Human respiratory syncytial virus (hRSV) is a significant cause of respiratory tract infections, particularly in young children and older adults. In this review, we aimed to comprehensively summarize what is known about the immune response to hRSV infection. We described the innate and adaptive immune components involved, including the recognition of RSV, the inflammatory response, the role of natural killer (NK) cells, antigen presentation, T cell response, and antibody production. Understanding the complex immune response to hRSV infection is crucial for developing effective interventions against this significant respiratory pathogen. Further investigations into the immune memory generated by hRSV infection and the development of strategies to enhance immune responses may hold promise for the prevention and management of hRSV-associated diseases. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2076-0817 |
Relation: |
https://www.mdpi.com/2076-0817/12/9/1118; https://doaj.org/toc/2076-0817 |
DOI: |
10.3390/pathogens12091118 |
Access URL: |
https://doaj.org/article/e303276dd5c44a659c1fd4cba2f74c08 |
Accession Number: |
edsdoj.303276dd5c44a659c1fd4cba2f74c08 |
Database: |
Directory of Open Access Journals |