Reshaping Our Knowledge: Advancements in Understanding the Immune Response to Human Respiratory Syncytial Virus

Bibliographic Details
Title: Reshaping Our Knowledge: Advancements in Understanding the Immune Response to Human Respiratory Syncytial Virus
Authors: Federica Attaianese, Sara Guiducci, Sandra Trapani, Federica Barbati, Lorenzo Lodi, Giuseppe Indolfi, Chiara Azzari, Silvia Ricci
Source: Pathogens, Vol 12, Iss 9, p 1118 (2023)
Publisher Information: MDPI AG, 2023.
Publication Year: 2023
Collection: LCC:Medicine
Subject Terms: immune response, RSV, syncytial respiratory virus, prevention strategy, Medicine
More Details: Human respiratory syncytial virus (hRSV) is a significant cause of respiratory tract infections, particularly in young children and older adults. In this review, we aimed to comprehensively summarize what is known about the immune response to hRSV infection. We described the innate and adaptive immune components involved, including the recognition of RSV, the inflammatory response, the role of natural killer (NK) cells, antigen presentation, T cell response, and antibody production. Understanding the complex immune response to hRSV infection is crucial for developing effective interventions against this significant respiratory pathogen. Further investigations into the immune memory generated by hRSV infection and the development of strategies to enhance immune responses may hold promise for the prevention and management of hRSV-associated diseases.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2076-0817
Relation: https://www.mdpi.com/2076-0817/12/9/1118; https://doaj.org/toc/2076-0817
DOI: 10.3390/pathogens12091118
Access URL: https://doaj.org/article/e303276dd5c44a659c1fd4cba2f74c08
Accession Number: edsdoj.303276dd5c44a659c1fd4cba2f74c08
Database: Directory of Open Access Journals
More Details
ISSN:20760817
DOI:10.3390/pathogens12091118
Published in:Pathogens
Language:English