Onward Virus Transmission after Measles Secondary Vaccination Failure
| Title: | Onward Virus Transmission after Measles Secondary Vaccination Failure |
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| Authors: | Isaac Tranter, Nicolas Smoll, Colleen L. Lau, Dusty-Lee Williams, Deborah Neucom, Donna Barnekow, Amalie Dyda |
| Source: | Emerging Infectious Diseases, Vol 30, Iss 9, Pp 1747-1754 (2024) |
| Publisher Information: | Centers for Disease Control and Prevention, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Medicine LCC:Infectious and parasitic diseases |
| Subject Terms: | measles, vaccination, vaccine-preventable diseases, secondary vaccination failure, viruses, vaccines, Medicine, Infectious and parasitic diseases, RC109-216 |
| More Details: | Measles in persons with secondary vaccination failure (SVF) may be less infectious than cases in unvaccinated persons. Our systematic review aimed to assess transmission risk for measles after SVF. We searched PubMed, Embase, and Web of Science databases from their inception dates. Inclusion criteria were articles describing persons who were exposed to measles-infected persons who had experienced SVF. Across the included 14 studies, >3,030 persons were exposed to measles virus from SVF cases, of whom 180 were susceptible, indicating secondary attack rates of 0%–6.25%. We identified 109 cases of SVF from the studies; 10.09% (n = 11) of case-patients transmitted the virus, resulting in 23 further cases and yielding an effective reproduction number of 0.063 (95% CI 0.0–0.5). These findings suggest a remarkably low attack rate for SVF measles cases, suggesting that, In outbreak situations, public health management of unvaccinated persons could be prioritized over persons with SVF. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1080-6040 1080-6059 |
| Relation: | https://wwwnc.cdc.gov/eid/article/30/9/24-0150_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059 |
| DOI: | 10.3201/eid3009.240150 |
| Access URL: | https://doaj.org/article/e2e0b48acbe94385a66d37a8a6351af5 |
| Accession Number: | edsdoj.2e0b48acbe94385a66d37a8a6351af5 |
| Database: | Directory of Open Access Journals |
| ISSN: | 10806040 10806059 |
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| DOI: | 10.3201/eid3009.240150 |
| Published in: | Emerging Infectious Diseases |
| Language: | English |