Bibliographic Details
| Title: |
Utility of an alpha-1 adrenergic agonist in the management of chylothorax: a case series and management algorithm |
| Authors: |
Ruben Peralta, Ahmed F. Ramzee, Zeenat Khuda Bakhsh, Ayman El-Menyar, Ahmed Ajaj, Hassan Al-Thani |
| Source: |
European Journal of Case Reports in Internal Medicine (2024) |
| Publisher Information: |
SMC MEDIA SRL, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Medicine |
| Subject Terms: |
chylothorax, α1-adrenergic agonist, chest, octreotide, algorithm, Medicine |
| More Details: |
Chylothorax is the accumulation of lymphatic fluid (chyle) within the pleural space. There are multiple causes, including traumatic and non-traumatic mechanisms. Trauma can cause disruption of the thoracic duct either by direct damage or indirect crushing or avulsion mechanisms. Non-traumatic causes include infections, inflammatory processes, malignancies, and iatrogenic injury (during surgery or central venous access). The traditional management of traumatic chylothorax has been either a conservative approach, including complete nil per os, or a low-fat diet with medium-chain triglyceride supplementation with the administration of somatostatin or its analog, octreotide, versus a surgical approach consisting of thoracic duct ligation. Recently a less invasive approach via thoracic duct embolization has gained popularity. There have been a few reports of the successful use of an alpha 1-adrenergic agonist (midodrine) as an adjunct in the conservative approach. We describe the utility of midodrine in three cases of chylothorax and propose a management algorithm. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2284-2594 |
| Relation: |
https://www.ejcrim.com/index.php/EJCRIM/article/view/4705; https://doaj.org/toc/2284-2594 |
| DOI: |
10.12890/2024_004705 |
| Access URL: |
https://doaj.org/article/a2dee86883684f2bb228b449b659ed6a |
| Accession Number: |
edsdoj.2dee86883684f2bb228b449b659ed6a |
| Database: |
Directory of Open Access Journals |
