Analysis of the effects of group progressive resistance training on inflammatory markers, cardiovascular fitness parameters, and respiratory function in elderly patients with chronic obstructive pulmonary disease
| Title: | Analysis of the effects of group progressive resistance training on inflammatory markers, cardiovascular fitness parameters, and respiratory function in elderly patients with chronic obstructive pulmonary disease |
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| Authors: | Chunyang Li, Yijia Sun |
| Source: | Journal of Medical Biochemistry, Vol 44, Iss 1, Pp 112-118 (2025) |
| Publisher Information: | Society of Medical Biochemists of Serbia, Belgrade, 2025. |
| Publication Year: | 2025 |
| Collection: | LCC:Biochemistry |
| Subject Terms: | chronic obstructive pulmonary disease, cardiopulmonary function, interleukin-8 (il-8), interleukin-18 (il-18), interleukin-6 (il-6), Biochemistry, QD415-436 |
| More Details: | Background: To investigate the effects of implementing group progressive resistance training on Maximal Oxygen consumption (VO2max), Maximum Ventilation per minute (VEmax), Maximal Oxygen pulse (O2pulsemax), Maximum Heart Rate (HRmax), and Modified Medical Research Council dyspnea scale (mMRC) in elderly patients with chronic obstructive pulmonary disease. Methods: A total number of 114 elderly patients with chronic obstructive pulmonary disease treated in the hospital from May 2022 to May 2024 were collected and divided into two groups based on different training methods. The conventional group (n=57) received routine rehabilitation training, while the organization group (n=57) received group progressive resistance training. Cardio - pulmonary Exercise Testing (CPET) parameters, serum inflammatory factors, lung function indicators, and mMRC score were compared between two groups before training, 2 weeks of training, and 4 weeks of training. Results: Before training, there was no significant difference between the two groups regarding training compliance, CPET parameters, inflammatory factors, and mMRC score. After 2-4 weeks of training, both groups showed improvements in training frequency, intensity, autonomous training, and increases in VO2MAX, VEmax, O2pulsemax, and HRmax. However, the organization group had higher scores in these areas and lower levels of inflammatory factors (IL-8, IL-18, IL-6, IL-12) and mMRC scores compared to the conventional group, with statistically significant differences (P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1452-8258 1452-8266 |
| Relation: | https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2025/1452-82582501112C.pdf; https://doaj.org/toc/1452-8258; https://doaj.org/toc/1452-8266 |
| DOI: | 10.5937/jomb0-52323 |
| Access URL: | https://doaj.org/article/2da65dc0320c453bba7d889e4c605405 |
| Accession Number: | edsdoj.2da65dc0320c453bba7d889e4c605405 |
| Database: | Directory of Open Access Journals |
| ISSN: | 14528258 14528266 |
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| DOI: | 10.5937/jomb0-52323 |
| Published in: | Journal of Medical Biochemistry |
| Language: | English |