Academic Journal
Multidisciplinary surgical treatment of clear-cell renal carcinoma with inferior vena cava tumor thrombus level III and IV: our experience during the past decade
| Title: | Multidisciplinary surgical treatment of clear-cell renal carcinoma with inferior vena cava tumor thrombus level III and IV: our experience during the past decade |
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| Authors: | Tvrtko Hudolin, Vladimir Ferenčak, Luka Penezić, Toni Zekulić, Tomislav Kuliš, Marjan Marić, Oliver Pavlović, Ahmad El-Saleh, Nikola Knežević, Eleonora Goluža, Bojan Biočina, Željko Kaštelan |
| Source: | Libri Oncologici, Vol 48, Iss 2-3, Pp 68-72 (2020) |
| Publisher Information: | University Hospital for Tumors, 2020. |
| Publication Year: | 2020 |
| Collection: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: | renal cell carcinoma, inferior vena cava, venous thrombosis, radical nephrectomy, cardiopulmonary bypass, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: | Patients with non-metastatic, stage T3 clear-cell renal cell cancer present a clinical challenge for urologists. The extent of tumor thrombus in inferior vena cava is the primary determinant of surgical procedure complexity. Level III and IV thrombi require the use of cardiopulmonary bypass and hypothermic arrest. Careful preoperative planning and a multidisciplinary approach are mandatory. In this paper, we report outcomes of 12 patients who were surgically treated in our center. The 29 months overall survival for all patients was 69%, while three patients died during follow-up. Of nine surviving patients, six are currently disease-free, whereas three had disease progression. Our study showed that carefully selected patients with clear-cell renal cell carcinoma with inferior vena cava tumor thrombus level III and IV could be successfully treated with an aggressive surgical approach. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0300-8142 2584-3826 |
| Relation: | https://hrcak.srce.hr/file/364240; https://doaj.org/toc/0300-8142; https://doaj.org/toc/2584-3826 |
| DOI: | 10.20471/LO.2020.48.02-03.12 |
| Access URL: | https://doaj.org/article/a2d965bc5285440e88564df8af85d119 |
| Accession Number: | edsdoj.2d965bc5285440e88564df8af85d119 |
| Database: | Directory of Open Access Journals |
| ISSN: | 03008142 25843826 |
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| DOI: | 10.20471/LO.2020.48.02-03.12 |
| Published in: | Libri Oncologici |
| Language: | English |