Academic Journal
The Diagnostic Value of PI-RADS v2.1 in Patients with a History of Transurethral Resection of the Prostate (TURP)
| Title: | The Diagnostic Value of PI-RADS v2.1 in Patients with a History of Transurethral Resection of the Prostate (TURP) |
|---|---|
| Authors: | Jiazhou Liu, Shihang Pan, Liang Dong, Guangyu Wu, Jiayi Wang, Yan Wang, Hongyang Qian, Baijun Dong, Jiahua Pan, Yinjie Zhu, Wei Xue |
| Source: | Current Oncology, Vol 29, Iss 9, Pp 6373-6382 (2022) |
| Publisher Information: | MDPI AG, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: | prostate cancer, transurethral resection of the prostate, multiparametric magnetic resonance imaging, prostate-specific antigen, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: | To explore the diagnostic value of the Prostate Imaging–Reporting and Data System version 2.1 (PI-RADS v2.1) for clinically significant prostate cancer (CSPCa) in patients with a history of transurethral resection of the prostate (TURP), we conducted a retrospective study of 102 patients who underwent systematic prostate biopsies with TURP history. ROC analyses and logistic regression analyses were performed to demonstrate the diagnostic value of PI-RADS v2.1 and other clinical characteristics, including PSA and free/total PSA (F/T PSA). Of 102 patients, 43 were diagnosed with CSPCa. In ROC analysis, PSA, F/T PSA, and PI-RADS v2.1 demonstrated significant diagnostic value in detecting CSPCa in our cohort (AUC 0.710 (95%CI 0.608–0.812), AUC 0.768 (95%CI 0.676–0.860), AUC 0.777 (95%CI 0.688–0.867), respectively). Further, PI-RADS v2.1 scores of the peripheral and transitional zones were analyzed separately. In ROC analysis, PI-RADS v2.1 remained valuable in identifying peripheral-zone CSPCa (AUC 0.780 (95%CI 0.665–0.854; p < 0.001)) while having limited capability in distinguishing transitional zone lesions (AUC 0.533 (95%CI 0.410–0.557; p = 0.594)). PSA and F/T PSA retain significant diagnostic value for CSPCa in patients with TURP history. PI-RADS v2.1 is reliable for detecting peripheral-zone CSPCa but has limited diagnostic value when assessing transitional zone lesions. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1718-7729 1198-0052 |
| Relation: | https://www.mdpi.com/1718-7729/29/9/502; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729 |
| DOI: | 10.3390/curroncol29090502 |
| Access URL: | https://doaj.org/article/e2ce815da4fc40deb93f85272f701256 |
| Accession Number: | edsdoj.2ce815da4fc40deb93f85272f701256 |
| Database: | Directory of Open Access Journals |
| Full text is not displayed to guests. | Login for full access. |
| ISSN: | 17187729 11980052 |
|---|---|
| DOI: | 10.3390/curroncol29090502 |
| Published in: | Current Oncology |
| Language: | English |