Gypmacrophin A, a Rare Pentacyclic Sesterterpenoid, Together with Three Depsides, Functioned as New Chemical Evidence for Gypsoplaca macrophylla (Zahlbr.) Timdal Identification
| Title: | Gypmacrophin A, a Rare Pentacyclic Sesterterpenoid, Together with Three Depsides, Functioned as New Chemical Evidence for Gypsoplaca macrophylla (Zahlbr.) Timdal Identification |
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| Authors: | Yuan-Fei Zhou, Hai-Xia Shi, Kun Hu, Jian-Wei Tang, Xing-Ren Li, Xue Du, Han-Dong Sun, Li-Song Wang, Jian-Xin Pu |
| Source: | Molecules, Vol 22, Iss 10, p 1675 (2017) |
| Publisher Information: | MDPI AG, 2017. |
| Publication Year: | 2017 |
| Collection: | LCC:Organic chemistry |
| Subject Terms: | Gypsoplacaceae, Gypsoplaca macrophylla, Sesterterpenoid, Identification, Organic chemistry, QD241-441 |
| More Details: | The phytochemical investigation on 1 g of materials from Gypsoplaca macrophylla (Zahlbr.) Timdal resulted in the discovery of gypmacrophin A, a rare pentacyclic sesterterpenoid; brialmontin III, a new polysubstituted depside and two known ones, brialmontins I and II. The structure and absolute configurations of gypmacrophin A were elucidated by spectroscopic analyses and computational methods. Gypmacrophin A showed weak inhibition of AchE with an IC50 value of 32.03 μM. The four compounds provided new chemical evidence for G. macrophylla identification. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1420-3049 22101675 |
| Relation: | https://www.mdpi.com/1420-3049/22/10/1675; https://doaj.org/toc/1420-3049 |
| DOI: | 10.3390/molecules22101675 |
| Access URL: | https://doaj.org/article/2b9acc11753a46e2b533ddcd10838a22 |
| Accession Number: | edsdoj.2b9acc11753a46e2b533ddcd10838a22 |
| Database: | Directory of Open Access Journals |
| ISSN: | 14203049 22101675 |
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| DOI: | 10.3390/molecules22101675 |
| Published in: | Molecules |
| Language: | English |