Bibliographic Details
| Title: |
Dilated perivascular spaces and steno-occlusive changes in children and adults with moyamoya disease |
| Authors: |
Min-Gyu Park, Jieun Roh, Sung-Ho Ahn, Jae Wook Cho, Kyung-Pil Park, Seung Kug Baik |
| Source: |
BMC Neurology, Vol 24, Iss 1, Pp 1-7 (2024) |
| Publisher Information: |
BMC, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Neurology. Diseases of the nervous system |
| Subject Terms: |
Moyamoya disease, Perivascular space, Glymphatic system, Cerebrovascular disorder, Neurology. Diseases of the nervous system, RC346-429 |
| More Details: |
Abstract Background Dilated perivascular spaces (DPVS), known as one of imaging markers in cerebral small vessel disease, may be found in patients with moyamoya disease (MMD). However, little is known about DPVS in MMD. The purpose of this study was to investigate the distribution pattern of dPVS in children and adults with MMD and determine whether it is related to steno-occlusive changes of MMD. Methods DPVS was scored in basal ganglia (BG) and white matter (WM) on T2-weighted imaging, using a validated 4-point semi-quantitative score. The degree of dPVS was classified as high (score > 2) or low (score ≤ 2) grade. The steno-occlusive changes on MR angiography (MRA) was scored using a validated MRA grading. Asymmetry of DPVS and MRA grading was defined as a difference of 1 grade or higher between hemispheres. Results Fifty-one patients with MMD (mean age 24.9 ± 21.1 years) were included. Forty-five (88.2%) patients had high WM-DPVS grade (degree 3 or 4). BG-DPVS was found in 72.5% of all patients and all were low grade (degree 1 or 2). The distribution patterns of DPVS degree in BG (P = 1.000) and WM (P = 0.767) were not different between child and adult groups. The asymmetry of WM-DPVS (26%) and MRA grade (42%) were significantly correlated to each other (Kendall’s tau-b = 0.604, P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2377 |
| Relation: |
https://doaj.org/toc/1471-2377 |
| DOI: |
10.1186/s12883-023-03520-z |
| Access URL: |
https://doaj.org/article/e2b48120ba7b468cbfb9f8b1c0ccea05 |
| Accession Number: |
edsdoj.2b48120ba7b468cbfb9f8b1c0ccea05 |
| Database: |
Directory of Open Access Journals |
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