Role of the notched unipolar electrogram in guiding catheter ablation of frequent premature ventricular contractions originating from the ventricular outflow tract
| Title: | Role of the notched unipolar electrogram in guiding catheter ablation of frequent premature ventricular contractions originating from the ventricular outflow tract |
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| Authors: | Li-Hong Huang, Ming-Yang Gao, Li-Jun Zeng, Bo-Qia Xie, Liang Shi, Yan-Jiang Wang, Xian-Dong Yin, Yu-Xing Wang, Xiao-Qing Liu, Ying Tian, Xin-Chun Yang, Xing-Peng Liu |
| Source: | Journal of International Medical Research, Vol 48 (2020) |
| Publisher Information: | SAGE Publishing, 2020. |
| Publication Year: | 2020 |
| Collection: | LCC:Medicine (General) |
| Subject Terms: | Medicine (General), R5-920 |
| More Details: | Objective To investigate the value of a notched unipolar electrogram (N-uniEGM) in confirming the origin of premature ventricular contractions originating from the ventricular outflow tract (VOT-PVC) during mapping and ablation procedures. Methods This retrospective study enrolled consecutive patients with symptomatic idiopathic frequent VOT-PVCs that underwent radiofrequency ablation. The characteristics of the uniEGM of the successful ablation targets were analysed. N-uniEGM was defined as the uniEGM presenting a QS morphology with ≥1 steep notches on the downstroke deflection. All patients were followed-up for 3 months post-ablation. Results The study enrolled 190 patients with a mean ± SD age of 49.0 ± 15.3 years. N-uniEGMs were recorded in 124 of 190 (65.3%) patients. The N-uniEGM distribution area was limited to a mean ± SD of 0.8 ± 0.4 cm 2 . N-uniEGM showed consistency with the outcomes of activation mapping and pace mapping. Patients with an N-uniEGM had an ablation success rate of 98.4% (122 of 124) and their ablation times were significantly shorter than those without an N-uniEGM (7.6 ± 3.8 s versus 15.8 ± 8.8 s, respectively). The sensitivity and specificity of N-uniEGM in predicting successful ablation of VOT-PVCs were 72.6% and 91.7%, respectively. Conclusion N-uniEGM was a highly specific and moderately sensitive predictor of successful radiofrequency ablation in patients with VOT-PVCs. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1473-2300 03000605 |
| Relation: | https://doaj.org/toc/1473-2300 |
| DOI: | 10.1177/0300060520977634 |
| Access URL: | https://doaj.org/article/d2a9aad369364a759221056d792eee3c |
| Accession Number: | edsdoj.2a9aad369364a759221056d792eee3c |
| Database: | Directory of Open Access Journals |
| ISSN: | 14732300 03000605 |
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| DOI: | 10.1177/0300060520977634 |
| Published in: | Journal of International Medical Research |
| Language: | English |