Academic Journal
Splenic cyst deroofing complicated with B lymphoma
| Title: | Splenic cyst deroofing complicated with B lymphoma |
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| Authors: | Iago Justo, Carlos Jiménez-Romero, Antonio Suárez, Pablo Vazquez, Enrique Revilla, Carmelo Loinaz, Mercedes Bernaldo de Quirós |
| Source: | World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-4 (2024) |
| Publisher Information: | BMC, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Surgery LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: | Splenic cyst, Splenic cell-B lymphoma, Fibrin associated large B-cell lymphomas, Surgery, RD1-811, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: | Abstract Background Splenic cysts are uncommon and very rarely malignant therefore their treatment isn’t standardized. In case of symptomatic cysts different surgical approaches have been suggested. Primary malignant lymphoma of the spleen comprises less than 1% of non-Hodgkin’s lymphomas. To our knowledge, only 203 cases of splenic large B-cell lymphoma (LBCL) have been reported to date and only 2 of them were fibrin-associated splenic cysts. Case presentation 27-year-old model with a 19 × 13 cm splenic cyst without data of malignancy in the preliminary study and therefore treated with laparoscopic deroofing. After histological diagnosis of LBCL with a fibrin/EBV-associated splenic pseudocyst, the patient received 4 cycles of Rituximab and a laparoscopic splenectomy was performed due to resurgence of the pseudocyst. No evidence of malignancy has been found during follow up (EBV viral load every 3 months during the first year, PET-CT every 6 months during the first year and annual afterwards) performed after the splenectomy. Discussion and conclusions The value of tumor markers and radiology for diagnosis of splenic cysts is put into question. Only 60 cases of Fibrin-associated LBCL (FA-LBCL) have been described in the literature therefore there are no treatment guidelines for them even though surgery together with systemic treatment has been the prevalent route with good results in most cases. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1477-7819 |
| Relation: | https://doaj.org/toc/1477-7819 |
| DOI: | 10.1186/s12957-024-03509-z |
| Access URL: | https://doaj.org/article/2a96e8f4ca334d5b9ffe562d84ad470a |
| Accession Number: | edsdoj.2a96e8f4ca334d5b9ffe562d84ad470a |
| Database: | Directory of Open Access Journals |
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| ISSN: | 14777819 |
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| DOI: | 10.1186/s12957-024-03509-z |
| Published in: | World Journal of Surgical Oncology |
| Language: | English |