Academic Journal
Morphometrics in three dimensional choroidal vessel models constructed from swept-source optical coherence tomography images
| Title: | Morphometrics in three dimensional choroidal vessel models constructed from swept-source optical coherence tomography images |
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| Authors: | Yukinori Sugano, Shunsuke Maeda, Yutaka Kato, Akihito Kasai, Shingo Tsuji, Masahiro Okamoto, Tetsuju Sekiryu |
| Source: | Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022) |
| Publisher Information: | Nature Portfolio, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Medicine, Science |
| More Details: | Abstract We created three types of vessel models: vessel volume, surface, and line models from swept-source optical coherence tomography images and tested experimentally calculated three-dimensional (3D) biomarkers. The choroidal volume (CVolume), surface area (VSurface), and vessel length-associated index (VLI) were measured. The calculated 3D parameters were the mean choroidal thickness, choroidal vascularity index (CVI), vessel length density index (VLDI), vessel length to the stromal (VL–S) ratio, surface-to-volume ratio (S–V ratio), and vessel diameter index (VDI). Cluster analysis showed that the parameters were classified into two clusters: one was represented by the VVolume including the CVolume, VSurface, CVI, S–V ratio, VLI, VDI, and subfoveal choroidal thickness and the other by the VL–S ratio including the VLDI. Regarding the regional distribution, the VVolume, CVolume, VSurface, CVI, VLI, VL–S ratio, and VDI at the foveal center were higher than at the parafovea (P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-022-17039-9 |
| Access URL: | https://doaj.org/article/c294392aef6849398bc98ffae105040f |
| Accession Number: | edsdoj.294392aef6849398bc98ffae105040f |
| Database: | Directory of Open Access Journals |
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| ISSN: | 20452322 |
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| DOI: | 10.1038/s41598-022-17039-9 |
| Published in: | Scientific Reports |
| Language: | English |