Geographical Requirements for the Applicability of the Results of the RACECAT Study to Other Stroke Networks

Bibliographic Details
Title: Geographical Requirements for the Applicability of the Results of the RACECAT Study to Other Stroke Networks
Authors: Florian A. F. Schuler, Marc Ribó, Nelly Dequatre‐Ponchelle, Jan Rémi, Tomas Dobrocky, Martina B. Goeldlin, Jan Gralla, Johannes Kaesmacher, Thomas R. Meinel, Pasquale Mordasini, David J. Seiffge, Urs Fischer, Marcel Arnold, Georg Kägi, Simon Jung
Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 20 (2023)
Publisher Information: Wiley, 2023.
Publication Year: 2023
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: drip‐and‐ship, mothership, population‐based, prehospital stroke triage, reperfusion therapy, stroke networks, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: Background The RACECAT (Transfer to the Closest Local Stroke Center vs Direct Transfer to Endovascular Stroke Center of Acute Stroke Patients With Suspected Large Vessel Occlusion in the Catalan Territory) trial was the first randomized trial addressing the prehospital triage of acute stroke patients based on the distribution of thrombolysis centers and intervention centers in Catalonia, Spain. The study compared the drip‐and‐ship with the mothership paradigm in regions where a local thrombolysis center can be reached faster than the nearest intervention center (equipoise region). The present study aims to determine the population‐based applicability of the results of the RACECAT study to 4 stroke networks with a different degree of clustering of the intervention centers (clustered, dispersed). Methods and Results Stroke networks were compared with regard to transport time saved for thrombolysis (under the drip‐and‐ship approach) and transport time saved for endovascular therapy (under the mothership approach). Population‐based transport times were modeled with a local instance of an openrouteservice server using open data from OpenStreetMap.The fraction of the population in the equipoise region differed substantially between clustered networks (Catalonia, 63.4%; France North, 87.7%) and dispersed networks (Southwest Bavaria, 40.1%; Switzerland, 40.0%). Transport time savings for thrombolysis under the drip‐and‐ship approach were more marked in clustered networks (Catalonia, 29 minutes; France North, 27 minutes) than in dispersed networks (Southwest Bavaria and Switzerland, both 18 minutes). Conclusions Infrastructure differences between stroke networks may hamper the applicability of the results of the RACECAT study to other stroke networks with a different distribution of intervention centers. Stroke networks should assess the population densities and hospital type/distribution in the temporal domain before applying prehospital triage algorithms to their specific setting.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2047-9980
Relation: https://doaj.org/toc/2047-9980
DOI: 10.1161/JAHA.123.029965
Access URL: https://doaj.org/article/e2910883363544fba700ab1a3064e403
Accession Number: edsdoj.2910883363544fba700ab1a3064e403
Database: Directory of Open Access Journals
More Details
ISSN:20479980
DOI:10.1161/JAHA.123.029965
Published in:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Language:English