Bibliographic Details
Title: |
White matter integrity in mice requires continuous myelin synthesis at the inner tongue |
Authors: |
Martin Meschkat, Anna M. Steyer, Marie-Theres Weil, Kathrin Kusch, Olaf Jahn, Lars Piepkorn, Paola Agüi-Gonzalez, Nhu Thi Ngoc Phan, Torben Ruhwedel, Boguslawa Sadowski, Silvio O. Rizzoli, Hauke B. Werner, Hannelore Ehrenreich, Klaus-Armin Nave, Wiebke Möbius |
Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022) |
Publisher Information: |
Nature Portfolio, 2022. |
Publication Year: |
2022 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Myelin is formed of proteins of long half-lives. The mechanisms of renewal of such a stable structure are unclear. Here, the authors show that myelin integrity requires continuous myelin synthesis at the inner tongue, contributing to the maintenance of a functional axon-myelin unit. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-022-28720-y |
Access URL: |
https://doaj.org/article/287e7feee643483fbef3a7725df08a2f |
Accession Number: |
edsdoj.287e7feee643483fbef3a7725df08a2f |
Database: |
Directory of Open Access Journals |