Prediction of Recurrence of Atrial Fibrillation After Radiofrequency Ablation by Frailty

Bibliographic Details
Title: Prediction of Recurrence of Atrial Fibrillation After Radiofrequency Ablation by Frailty
Authors: Ruochen Xu, Yan Dong, Nishant Yadav, Qiushi Chen, Kejiang Cao, Fengxiang Zhang
Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 14, Iss 6 (2025)
Publisher Information: Wiley, 2025.
Publication Year: 2025
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: ablation, atrial fibrillation, frailty, recurrence, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: Background Previous studies have shown that frailty increases the risk of new‐onset atrial fibrillation (AF). However, little is known about the association between frailty and the recurrence of AF after radiofrequency ablation. The objective of this study was to investigate the association between frailty and the recurrence in patients with AF who had undergone radiofrequency ablation. Methods and Results A total of 450 patients >50 years of age with symptomatic drug‐refractory AF who had undergone catheter ablation for the first time were retrospectively enrolled. Frailty status was evaluated by the 11‐factor modified frailty index and 5‐factor modified frailty index. Recurrence was defined as any documented atrial tachyarrhythmia lasting >30 seconds after a 3‐month blanking period without any antiarrhythmic drugs during postablation follow‐up. Patients in the frail group were older, and had a higher CHA2DS2‐VASc score, HAS‐BLED score, left atrial diameter, and a higher proportion of comorbidities than those in the nonfrail group. Circumferential pulmonary vein isolation was successfully done in all of the patients. During a median follow‐up of 12 months, recurrence was recorded in 98 (21.8%) patients (paroxysmal AF, 20.6%; persistent AF, 23.2%). The Kaplan‐Meier analysis showed that the survival rate of freedom from atrial tachyarrhythmias in the frail group was lower than that in nonfrail groups (log‐rank P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2047-9980
Relation: https://doaj.org/toc/2047-9980
DOI: 10.1161/JAHA.124.038044
Access URL: https://doaj.org/article/28662aa728244238b996ff7424d6e7d5
Accession Number: edsdoj.28662aa728244238b996ff7424d6e7d5
Database: Directory of Open Access Journals
More Details
ISSN:20479980
DOI:10.1161/JAHA.124.038044
Published in:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Language:English