Bibliographic Details
| Title: |
Cluster of differentiation 14 and toll-like receptor 4 are involved in the anti-inflammatory effects of tyrosol |
| Authors: |
Chao-Yuan Chang, I-Tao Huang, Hung-Jen Shih, Ya-Ying Chang, Ming-Chang Kao, Ping-Chen Shih, Chun-Jen Huang |
| Source: |
Journal of Functional Foods, Vol 53, Iss , Pp 93-104 (2019) |
| Publisher Information: |
Elsevier, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Nutrition. Foods and food supply |
| Subject Terms: |
CD14, TLR4, MyD88, TRIF, RAW264.7 cells, Nutrition. Foods and food supply, TX341-641 |
| More Details: |
We investigated effects of tyrosol on upstream pathway regulating lipopolysaccharide (LPS)-induced inflammatory response, including cluster of differentiation 14 (CD14)-mediated LPS–macrophage binding, toll-like receptor 4 (TLR4)/myeloid differentiation factor 2 (MD2) expression and subsequent myeloid differentiation primary response gene 88 (MyD88) and TIR-domain-containing adapter-inducing interferon-β (TRIF) recruitments. Flow cytometry revealed that, compared with LPS-treated RAW264.7 cells (LPS group), those treated with LPS and tyrosol (1.2 mM) [LPS+T(1.2) group] demonstrated lower LPS–macrophage binding and membrane-bound CD14 (mCD14) and TLR4/MD2 expression (all p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1756-4646 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1756464618306406; https://doaj.org/toc/1756-4646 |
| DOI: |
10.1016/j.jff.2018.12.011 |
| Access URL: |
https://doaj.org/article/283c47e91a864c1b9fb7a4458bcf4a5b |
| Accession Number: |
edsdoj.283c47e91a864c1b9fb7a4458bcf4a5b |
| Database: |
Directory of Open Access Journals |
