Bibliographic Details
| Title: |
Sleep-like cortical dynamics during wakefulness and their network effects following brain injury |
| Authors: |
Marcello Massimini, Maurizio Corbetta, Maria V. Sanchez-Vives, Thomas Andrillon, Gustavo Deco, Mario Rosanova, Simone Sarasso |
| Source: |
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024) |
| Publisher Information: |
Nature Portfolio, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Abstract By connecting old and recent notions, different spatial scales, and research domains, we introduce a novel framework on the consequences of brain injury focusing on a key role of slow waves. We argue that the long-standing finding of EEG slow waves after brain injury reflects the intrusion of sleep-like cortical dynamics during wakefulness; we illustrate how these dynamics are generated and how they can lead to functional network disruption and behavioral impairment. Finally, we outline a scenario whereby post-injury slow waves can be modulated to reawaken parts of the brain that have fallen asleep to optimize rehabilitation strategies and promote recovery. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-024-51586-1 |
| Access URL: |
https://doaj.org/article/280a12bd41064d9ab9bc5738df66650f |
| Accession Number: |
edsdoj.280a12bd41064d9ab9bc5738df66650f |
| Database: |
Directory of Open Access Journals |
