Title: |
Dual roles and evolutionary implications of P26/poxin in antagonizing intracellular cGAS-STING and extracellular melanization immunity |
Authors: |
Mengyi Yin, Wenhua Kuang, Qianran Wang, Xi Wang, Chuanfei Yuan, Zhe Lin, Huanyu Zhang, Fei Deng, Haobo Jiang, Peng Gong, Zhen Zou, Zhihong Hu, Manli Wang |
Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022) |
Publisher Information: |
Nature Portfolio, 2022. |
Publication Year: |
2022 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Poxins or P26 have been identified as inhibitors of cGAS-STING mediated innate immunity. Here, the authors describe an independently evolved antiviral function of P26 in suppressing melanization, an insect immune response. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-022-34761-0 |
Access URL: |
https://doaj.org/article/27f6c3d006374a15905c1dede99eb25a |
Accession Number: |
edsdoj.27f6c3d006374a15905c1dede99eb25a |
Database: |
Directory of Open Access Journals |