Effects of vitamin D3 supplementation on the recovery of hospitalized burn patients: a randomized double-blind controlled trial
| Title: | Effects of vitamin D3 supplementation on the recovery of hospitalized burn patients: a randomized double-blind controlled trial |
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| Authors: | Elahe Ghadimi, Roozbeh Rahbar, Elham Jafarzade, Anahita Mansoori |
| Source: | BMC Nutrition, Vol 11, Iss 1, Pp 1-11 (2025) |
| Publisher Information: | BMC, 2025. |
| Publication Year: | 2025 |
| Collection: | LCC:Nutrition. Foods and food supply LCC:Food processing and manufacture LCC:Medicine (General) |
| Subject Terms: | Burn patients, Vitamin D supplementation, Wound healing, Wound infection, Scar formation, Nutrition. Foods and food supply, TX341-641, Food processing and manufacture, TP368-456, Medicine (General), R5-920 |
| More Details: | Abstract Background Burn patients, due to their damaged skin, may not be able to synthesize vitamin D. In this study, we aimed to evaluate the effects of vitamin D supplementation on the recovery of hospitalized burn patients. Methods Fifty-four patients participated in a randomized controlled trial. Eighteen patients were randomly assigned to group C (control, received gelatin soft gel as placebo), 18 patients to group D1 (received 1000 IU/day vitamin D), and 18 patients to group D2 (received 3000 IU/day vitamin D). After supplementation, wound biopsy and blood samples were obtained from the patients. Weight, height, 25(OH)D level, wound healing, scar formation, quality of pain, and blood parameters were evaluated. Results There were no significant differences in the serum vitamin D levels between the groups at admission (P = 0.52), and 81.5% of the participants were deficient, with a noteworthy increase during study in supplemented groups (P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2055-0928 |
| Relation: | https://doaj.org/toc/2055-0928 |
| DOI: | 10.1186/s40795-025-01024-2 |
| Access URL: | https://doaj.org/article/27eb60fd263942448d201214adb277b0 |
| Accession Number: | edsdoj.27eb60fd263942448d201214adb277b0 |
| Database: | Directory of Open Access Journals |
| ISSN: | 20550928 |
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| DOI: | 10.1186/s40795-025-01024-2 |
| Published in: | BMC Nutrition |
| Language: | English |