Bibliographic Details
| Title: |
Topical riboflavin versus 5-aminolevulinic acid photodynamic therapy for the treatment of mild to moderate acne: A split-face randomized study |
| Authors: |
Aijia Ding, Li Shi, Feng Jiang, Chong Wang, Jianglin Zhang |
| Source: |
Photodiagnosis and Photodynamic Therapy, Vol 51, Iss , Pp 104449- (2025) |
| Publisher Information: |
Elsevier, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Medicine (General) |
| Subject Terms: |
Riboflavin, 5-aminolevulinic acid, Photodynamic therapy, Acne vulgaris, Randomized study, Medicine (General), R5-920 |
| More Details: |
Background: ALA-PDT has been widely used in mild to moderate acne vulgaris worldwide. However, very few studies used riboflavin-PDT to treat acne vulgaris. Objective: To investigate the efficacy and adverse events of riboflavin-PDT to treat mild to moderate facial acne, and compare it with ALA-PDT on a non-inferiority basis. Methods: 33 eligible patients were enrolled, and 30 patients completed follow-up. Either side of the face was assigned randomly to riboflavin or ALA blue-light-PDT. Patients received 3 sessions of PDT in 1-week intervals and were followed up at weeks 4, 6, and 10. Results: Both ALA and riboflavin-PDT significantly reduced non-inflammatory and inflammatory lesions at weeks 4, 6, and 10 compared to baseline (P all |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1572-1000 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S157210002400485X; https://doaj.org/toc/1572-1000 |
| DOI: |
10.1016/j.pdpdt.2024.104449 |
| Access URL: |
https://doaj.org/article/26e3612c4b944bcc863790df4897acb3 |
| Accession Number: |
edsdoj.26e3612c4b944bcc863790df4897acb3 |
| Database: |
Directory of Open Access Journals |
