Calreticulin arms NK cells against leukemia

Bibliographic Details
Title:	Calreticulin arms NK cells against leukemia
Authors:	Jitka Fucikova, Justin P. Kline, Lorenzo Galluzzi, Radek Spisek
Source:	OncoImmunology, Vol 9, Iss 1 (2020)
Publisher Information:	Taylor & Francis Group, 2020.
Publication Year:	2020
Collection:	LCC:Immunologic diseases. Allergy LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Subject Terms:	anticancer immunity, cd80, ccr7, il15, immunogenic cell death, mhc class ii, type i ifn, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
More Details:	Calreticulin (CALR) exposed on the surface of cancer cells succumbing to therapy delivers robust phagocytic signals that support the activation of adaptive anticancer immune responses. Recent data from our group demonstrate that spontaneous CARL exposure on leukemic blasts also supports innate anticancer immunity by natural killer (NK) cells via an indirect mechanism relying on myeloid CD11c+CD14+ cells.
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	2162-402X 2162402X
Relation:	https://doaj.org/toc/2162-402X
DOI:	10.1080/2162402X.2019.1671763
Access URL:	https://doaj.org/article/26a70ffa3ff6410c91d79bb9550202d5
Accession Number:	edsdoj.26a70ffa3ff6410c91d79bb9550202d5
Database:	Directory of Open Access Journals