Bibliographic Details
| Title: |
Incidence, Morbidity, and Mortality of Achalasia: A Nationwide, Population-Based Cohort Study in South Korea |
| Authors: |
Ga Hee Kim, Hyungchul Park, Kee Wook Jung, Min-Ju Kim, Ye-Jee Kim, Ji Min Lee, Bong Eun Lee, Yang Won Min, Jeong Hwan Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Hyun Jin Kim, Big Data Study Group Under the Korean Society of Neurogastroenterology and Motility |
| Source: |
Gut and Liver, Vol 17, Iss 6, Pp 894-904 (2023) |
| Publisher Information: |
Gastroenterology Council for Gut and Liver, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Diseases of the digestive system. Gastroenterology |
| Subject Terms: |
esophageal achalasia, esophagus, aspiration pneumonia, esophageal neoplasms, Diseases of the digestive system. Gastroenterology, RC799-869 |
| More Details: |
Background/Aims: Although an association between achalasia and esophageal cancer has been reported, whether achalasia confers a substantial increase in mortality is unknown. Moreover, the causes of death related to achalasia have not been investigated. We performed this nationwide, population-based cohort study on achalasia because no such study has been performed since the introduction of high-resolution manometry in 2008. Methods: This study was performed using data extracted from the Korean National Health Insurance Service database, covering a 9-year period from 2009 to 2017. Control participants without a diagnostic code for achalasia were randomly selected and matched by sex and birth year at a case-to-control ratio of 1:4. Data on the cause of death from Statistics Korea were also analyzed. Results: The overall incidence of achalasia was 0.68 per 100,000 person-years, and the prevalence was 6.46 per 100,000 population. Patients with achalasia (n=3,063) had significantly higher adjusted hazard ratio (aHR) for esophageal cancer (aHR, 3.40; 95% confidence interval [CI], 1.25 to 9.22; p=0.017), pneumonia (aHR, 2.30; 95% CI, 1.89 to 2.81; p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1976-2283 |
| Relation: |
http://gutnliver.org/journal/view.html?doi=10.5009/gnl220334; https://doaj.org/toc/1976-2283 |
| DOI: |
10.5009/gnl220334 |
| Access URL: |
https://doaj.org/article/26a1d98f293c4ee4b7ec6cefee565257 |
| Accession Number: |
edsdoj.26a1d98f293c4ee4b7ec6cefee565257 |
| Database: |
Directory of Open Access Journals |
