Keeping immune checkpoint inhibitor myocarditis in check: advanced circulatory mechanical support as a bridge to recovery

Bibliographic Details
Title: Keeping immune checkpoint inhibitor myocarditis in check: advanced circulatory mechanical support as a bridge to recovery
Authors: Ashley F. Stein‐Merlob, Jeffrey J. Hsu, Bradley Colton, Christopher J. Berg, Allison Ferreira, Megan M. Price, Zev Wainberg, Arnold S. Baas, Mario C. Deng, Rushi V. Parikh, Eric H. Yang
Source: ESC Heart Failure, Vol 8, Iss 5, Pp 4301-4306 (2021)
Publisher Information: Wiley, 2021.
Publication Year: 2021
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: Cardiomyopathy, Cardiac assist device, Acute heart failure, Immune checkpoint inhibitor myocarditis, Cardiooncology, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: Abstract Immune checkpoint inhibitor (ICI)‐associated myocarditis is a rare, potentially life‐threatening complication of immunotherapy. We report a case of a 60‐year‐old female with a history of colorectal cancer treated with nivolumab immunotherapy who presented with new cardiomyopathy complicated by cardiogenic shock and ventricular arrhythmias. Treatment of ICI‐associated myocarditis requires aggressive immunosuppression and supportive therapy. In this case, the patient required advanced mechanical circulatory support as a bridge to recovery. This case highlights the complexity of diagnosis, haemodynamic management, and treatment of fulminant ICI myocarditis.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2055-5822
Relation: https://doaj.org/toc/2055-5822
DOI: 10.1002/ehf2.13545
Access URL: https://doaj.org/article/e267b508b25d4eb88f9662f24c2173a2
Accession Number: edsdoj.267b508b25d4eb88f9662f24c2173a2
Database: Directory of Open Access Journals
More Details
ISSN:20555822
DOI:10.1002/ehf2.13545
Published in:ESC Heart Failure
Language:English