Academic Journal
Structural insights into the function of ZRANB3 in replication stress response
| Title: | Structural insights into the function of ZRANB3 in replication stress response |
|---|---|
| Authors: | Marek Sebesta, Christopher D. O. Cooper, Antonio Ariza, Christopher J. Carnie, Dragana Ahel |
| Source: | Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017) |
| Publisher Information: | Nature Portfolio, 2017. |
| Publication Year: | 2017 |
| Collection: | LCC:Science |
| Subject Terms: | Science |
| More Details: | ZRANB3 (Zinc-finger, RAN-Binding domain containing 3) is a structure-specific endonuclease that is recruited to DNA breaks and stressed replication forks. Here the authors present the crystal structure of the ZRANB3 endonuclease domain and analyse how ZRANB3 is regulated by the DNA clamp PCNA. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2041-1723 18735606 |
| Relation: | https://doaj.org/toc/2041-1723 |
| DOI: | 10.1038/ncomms15847 |
| Access URL: | https://doaj.org/article/e255a9bc2f6248c5a18735606cd0c8fe |
| Accession Number: | edsdoj.255a9bc2f6248c5a18735606cd0c8fe |
| Database: | Directory of Open Access Journals |
| ISSN: | 20411723 18735606 |
|---|---|
| DOI: | 10.1038/ncomms15847 |
| Published in: | Nature Communications |
| Language: | English |