Bibliographic Details
Title: |
Synergistic Pd/Cu-catalyzed enantioselective Csp2–F bond alkylation of fluoro-1,3-dienes with aldimine esters |
Authors: |
Huimin Yu, Qinglong Zhang, Weiwei Zi |
Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022) |
Publisher Information: |
Nature Portfolio, 2022. |
Publication Year: |
2022 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Due to high bond dissociation energies of C(sp2)–F bonds, using fluorinated compounds in C(sp2)–C(sp3) cross-coupling is difficult. Here the authors report a protocol for enantioselective C(sp2)–C(sp3) coupling of dienyl fluorides with aldimine esters, enabled by synergistic copper and palladium catalysis. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-022-30152-7 |
Access URL: |
https://doaj.org/article/25080896c7e6437abba844e428c7d828 |
Accession Number: |
edsdoj.25080896c7e6437abba844e428c7d828 |
Database: |
Directory of Open Access Journals |