Bibliographic Details
| Title: |
Epidemiology and risk factors for mortality in critically ill patients with pancreatic infection |
| Authors: |
Marie Dejonckheere, Massimo Antonelli, Kostoula Arvaniti, Koen Blot, Ben CreaghBrown, Dylan W. de Lange, Jan De Waele, Mieke Deschepper, Yalim Dikmen, George Dimopoulos, Christian Eckmann, Guy Francois, Massimo Girardis, Despoina Koulenti, Sonia Labeau, Jeffrey Lipman, Fernando Lipovestky, Emilio Maseda, Philippe Montravers, Adam Mikstacki, JoseArtur Paiva, Cecilia Pereyra, Jordi Rello, JeanFrancois Timsit, Dirk Vogelaers, Stijn Blot |
| Source: |
Journal of Intensive Medicine, Vol 4, Iss 1, Pp 81-93 (2024) |
| Publisher Information: |
Elsevier, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Medical emergencies. Critical care. Intensive care. First aid |
| Subject Terms: |
Pancreatic infection, Intensive care unit, Mortality, Intra-abdominal infection, Sepsis, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9 |
| More Details: |
Background: The AbSeS-classification defines specific phenotypes of patients with intra-abdominal infection based on the (1) setting of infection onset (community-acquired, early onset, or late-onset hospital-acquired), (2) presence or absence of either localized or diffuse peritonitis, and (3) severity of disease expression (infection, sepsis, or septic shock). This classification system demonstrated reliable risk stratification in intensive care unit (ICU) patients with intra-abdominal infection. This study aimed to describe the epidemiology of ICU patients with pancreatic infection and assess the relationship between the components of the AbSeS-classification and mortality. Methods: This was a secondary analysis of an international observational study (“AbSeS”) investigating ICU patients with intra-abdominal infection. Only patients with pancreatic infection were included in this analysis (n=165). Mortality was defined as ICU mortality within 28 days of observation for patients discharged earlier from the ICU. Relationships with mortality were assessed using logistic regression analysis and reported as odds ratio (OR) and 95% confidence interval (CI). Results: The overall mortality was 35.2% (n=58). The independent risk factors for mortality included older age (OR=1.03, 95% CI: 1.0 to 1.1 P=0.023), localized peritonitis (OR=4.4, 95% CI: 1.4 to 13.9 P=0.011), and persistent signs of inflammation at day 7 (OR=9.5, 95% CI: 3.8 to 23.9, P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2667-100X |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2667100X23000464; https://doaj.org/toc/2667-100X |
| DOI: |
10.1016/j.jointm.2023.06.004 |
| Access URL: |
https://doaj.org/article/249eeffe67194733a4def7f60b4cd1b1 |
| Accession Number: |
edsdoj.249eeffe67194733a4def7f60b4cd1b1 |
| Database: |
Directory of Open Access Journals |
