Bioanalogues in the treatment of rheumatoid arthritis: current status of the problem

Bibliographic Details
Title:	Bioanalogues in the treatment of rheumatoid arthritis: current status of the problem
Authors:	N. V. Chichasova, A. M. Lila
Source:	Современная ревматология, Vol 18, Iss 6, Pp 98-106 (2024)
Publisher Information:	IMA-PRESS LLC, 2024.
Publication Year:	2024
Collection:	LCC:Medicine
Subject Terms:	rheumatoid arthritis, biologic disease-modifying antirheumatic drug, etanercept, biosimilar gp2015, nocebo, Medicine
More Details:	The article discusses the use of bioanalogues (BAs) in the treatment of rheumatoid arthritis using the example of the comparable efficacy, tolerability and immunogenicity of the original biologic disease-modifying antirheumatic drug (bDMARD) etanercept (ETC) and its BA GP-2015. We discuss the maintenance of the improvement achieved when switching from the original ETC to BA. Recommendations of international experts and preliminary recommendations of the Association of Rheumatologists of Russia on the use of BA are given. The frequency of development and negative consequences of the nocebo effect when switching patients to BA are described. Data from randomized controlled trials and clinical practice on the safety of switching patients from original biologics to BA are presented. The economic benefits of introducing BA into the clinical practice of rheumatologists in Europe and Russian Federation are considered.
Document Type:	article
File Description:	electronic resource
Language:	Russian
ISSN:	1996-7012 2310-158X
Relation:	https://mrj.ima-press.net/mrj/article/view/1673; https://doaj.org/toc/1996-7012; https://doaj.org/toc/2310-158X
DOI:	10.14412/1996-7012-2024-6-98-106
Access URL:	https://doaj.org/article/a23e8de8b84341e0aa3fa5e53c7b8e84
Accession Number:	edsdoj.23e8de8b84341e0aa3fa5e53c7b8e84
Database:	Directory of Open Access Journals

More Details
ISSN:	19967012 2310158X
DOI:	10.14412/1996-7012-2024-6-98-106
Published in:	Современная ревматология
Language:	Russian