| Title: |
Associations of Serum Albumin With Disability in Activities of Daily Living, Mobility and Objective Physical Functioning Regardless of Vitamin D: Cross-Sectional Findings From the Chinese Longitudinal Healthy Longevity Survey |
| Authors: |
Xueqin Li, Xingqi Cao, Zhimin Ying, Jingyun Zhang, Xiaoyi Sun, Emiel O. Hoogendijk, Zuyun Liu |
| Source: |
Frontiers in Nutrition, Vol 9 (2022) |
| Publisher Information: |
Frontiers Media S.A., 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Nutrition. Foods and food supply |
| Subject Terms: |
serum albumin, activities of daily living, mobility, objective physical functioning, disability, older adult, Nutrition. Foods and food supply, TX341-641 |
| More Details: |
ObjectiveTo examine the associations of serum albumin, a nutrition indicator, with disability in activities of daily living (ADL), mobility, and objective physical functioning among Chinese older adults.Materials and MethodsCross-sectional data of 2233 older adults (≥65 years) who participated in the 2011/2012 main survey of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) and the 2012 biomarker sub-study was used. Serum albumin was measured by immunoturbidimetric assay. Physical functioning included subjectively (ADL and mobility) and objectively measured disability (standing up from a chair, picking up a book from the floor, and turning around 360°). Multivariable logistic regression models were performed.ResultsAfter adjusting for age and sex, compared with participants in the lowest quartile group of serum albumin, those in the highest quartile group had 45% lower odds of disability in ADL (odds ratio [OR]: 0.55; 95% confidence interval [CI]: 0.38, 0.80); 48% lower odds of disability in mobility (OR: 0.52; 95% CI: 0.38, 0.71); 46% lower odds of disability in standing up from a chair (OR: 0.54; 95% CI: 0.34, 0.85); and 37% lower odds of disability in picking up a book from the floor (OR: 0.63; 95% CI: 0.40, 0.97). We did not observe a statistically significant interaction effect between serum albumin and vitamin D on disability in physical functioning.ConclusionSerum albumin level was associated with physical functioning among Chinese older adults, regardless of vitamin D level. The findings indicate that appropriate management of poor nutritional status, in particular low serum albumin levels, may contribute to maintaining physical functioning in older adults. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2296-861X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fnut.2022.809499/full; https://doaj.org/toc/2296-861X |
| DOI: |
10.3389/fnut.2022.809499 |
| Access URL: |
https://doaj.org/article/de23c566011f4906aea98f897297b75b |
| Accession Number: |
edsdoj.23c566011f4906aea98f897297b75b |
| Database: |
Directory of Open Access Journals |
