Bibliographic Details
| Title: |
High-sensitivity colorimetric sensor based on oxidase-like Mn3O4 nanozyme for Cys detection |
| Authors: |
Junting Liang, Dihan Duan, Lubing Sun, Jinming Li, Mengke Wang, Ziyi Chang, Rick F. Thorne, Chuanliang Chen, Demin Duan |
| Source: |
Sensors and Actuators Reports, Vol 9, Iss , Pp 100296- (2025) |
| Publisher Information: |
Elsevier, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Instruments and machines |
| Subject Terms: |
Oxidase-like nanozyme, Mn3O4, Colorimetric sensor, Cysteine, Instruments and machines, QA71-90 |
| More Details: |
Cysteine (Cys) is essential for numerous physiological processes and play a vital role in disease diagnostics, underscoring the necessity for effective and sensitive detection techniques for Cys. In this research, we introduce an ultrasensitive colorimetric approach based on oxidase-like Mn3O4 nanozymes. The nanozymes were synthesized through a straightforward wet chemical method and displayed a flower-like globular morphology, showing remarkable oxidase-like catalytic performance with a low Km value of 0.1896 mM and a high Vmax of 2.8 × 10⁻⁷ M s⁻¹. By leveraging the outstanding catalytic activities of Mn3O4 nanozymes and optimizing the TMB concentration, we developed a novel and sensitive colorimetric sensor for Cys detection. Experimental results indicated a detection range for Cys between 0.5 and 45 μM, with a lower limit of detection (LOD) of 0.02636 μM. This established method for detecting Cys reveals significant promise for the advancement of effective sensing systems. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2666-0539 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2666053925000165; https://doaj.org/toc/2666-0539 |
| DOI: |
10.1016/j.snr.2025.100296 |
| Access URL: |
https://doaj.org/article/eec23790b7fb4c0fb7851291f4ddc0d3 |
| Accession Number: |
edsdoj.23790b7fb4c0fb7851291f4ddc0d3 |
| Database: |
Directory of Open Access Journals |
