To do or not to do; dilemma of intra-arterial revascularization in acute ischemic stroke.

Bibliographic Details
Title: To do or not to do; dilemma of intra-arterial revascularization in acute ischemic stroke.
Authors: Joon-Tae Kim, Suk-Hee Heo, Ji Sung Lee, Myeong-Ho Park, Dong-Seok Oh, Kang-Ho Choi, Ihn-Gyu Kim, Yeon Soo Ha, Hyuk Chang, In Sung Choo, Seong Hwan Ahn, Seul-Ki Jeong, Byoung-Soo Shin, Man-Seok Park, Ki-Hyun Cho
Source: PLoS ONE, Vol 9, Iss 6, p e99261 (2014)
Publisher Information: Public Library of Science (PLoS), 2014.
Publication Year: 2014
Collection: LCC:Medicine
LCC:Science
Subject Terms: Medicine, Science
More Details: There has still been lack of evidence for definite imaging criteria of intra-arterial revascularization (IAR). Therefore, IAR selection is left largely to individual clinicians. In this study, we sought to investigate the overall agreement of IAR selection among different stroke clinicians and factors associated with good agreement of IAR selection.From the prospectively registered data base of a tertiary hospital, we identified consecutive patients with acute ischemic stroke. IAR selection based on the provided magnetic resonance imaging (MRI) results and clinical information were independently performed by 5 independent stroke physicians currently working at 4 different university hospitals. MRI results were also reviewed by 2 independent experienced neurologists blinded to clinical data and physicians' IAR selection. The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) was calculated on initial DWI and MTT. We arbitrarily used ASPECTS differences between DWI and MTT (D-M ASPECTS) to quantitatively evaluate mismatch.The overall interobserver agreement of IAR selection was fair (kappa = 0.398). In patients with DWI-ASPECTS >6, interobserver agreement was moderate to substantial (0.398-0.620). In patients with D-M ASPECTS >4, interobserver agreement was moderate to almost perfect (0.532-1.000). Patients with higher DWI or D-M ASPECTS had better agreement of IAR selection.Our study showed that DWI-ASPSECTS >6 and D-M ASPECTS >4 had moderate to substantial agreement of IAR selection among different stroke physicians. However, there is still poor agreement as to whether IAR should not be performed in patients with lower DWI and D-M ASPECTS.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1932-6203
Relation: http://europepmc.org/articles/PMC4048270?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0099261
Access URL: https://doaj.org/article/aec2329e47904eb3b7a759b57fcfb6ba
Accession Number: edsdoj.2329e47904eb3b7a759b57fcfb6ba
Database: Directory of Open Access Journals
More Details
ISSN:19326203
DOI:10.1371/journal.pone.0099261
Published in:PLoS ONE
Language:English