The role of liver microenvironment cells in colorectal cancer liver metastasis

Bibliographic Details
Title: The role of liver microenvironment cells in colorectal cancer liver metastasis
Authors: ZHAO Yiming, WU Zong, WANG Lu
Source: Waike lilun yu shijian, Vol 29, Iss 02, Pp 126-131 (2024)
Publisher Information: Editorial Office of Journal of Surgery Concepts & Practice, 2024.
Publication Year: 2024
Collection: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
LCC:Surgery
Subject Terms: colorectal cancer liver metastasis, tumor microenvironment, hepatic stellate cell(hepsc), liver sinusoidal endothelial cell(lsec), kupffer cell(kc), neutrophil, macrophage, myeloid-derived suppressor cell(mdsc), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Surgery, RD1-811
More Details: The liver is the most common site of metastasis in patients with colorectal cancer(CRC). The liver microenvironment is a diverse assemblage of cells, which has their own unique biological characteristics and functions, supplemented by the interaction between cells, which jointly regulate the tumor microenvironment and play significant role in the occurrence and development of CRC liver metastasis. Consequently, a thorough investigation of the molecular mechanisms underlying CRC liver metastasis is imperative for comprehension of tumor progression, prediction of metastasis risk, and the development of innovative therapeutic strategy. This paper delved into the cellular constituents of the liver tumor microenvironment, elucidating the roles and influences of diverse cell types in the process of CRC liver metastasis, offering fresh insights and strategies for the diagnosis and management of CRC liver metastasis.
Document Type: article
File Description: electronic resource
Language: Chinese
ISSN: 1007-9610
Relation: https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1719829405203-340292144.pdf; https://doaj.org/toc/1007-9610
DOI: 10.16139/j.1007-9610.2024.02.06
Access URL: https://doaj.org/article/a222f7371f7d411191d467babd27b87b
Accession Number: edsdoj.222f7371f7d411191d467babd27b87b
Database: Directory of Open Access Journals
More Details
ISSN:10079610
DOI:10.16139/j.1007-9610.2024.02.06
Published in:Waike lilun yu shijian
Language:Chinese