Academic Journal
Global, regional and national trends in incidence and mortality of pertussis from 1990 to 2021 and the comparison before and during COVID-19: A modelling analysis
| Title: | Global, regional and national trends in incidence and mortality of pertussis from 1990 to 2021 and the comparison before and during COVID-19: A modelling analysis |
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| Authors: | Shimo Zhang, Sijia Wang, Jue Liu |
| Source: | Journal of Infection and Public Health, Vol 18, Iss 4, Pp 102696- (2025) |
| Publisher Information: | Elsevier, 2025. |
| Publication Year: | 2025 |
| Collection: | LCC:Infectious and parasitic diseases LCC:Public aspects of medicine |
| Subject Terms: | Pertussis, GBD 2021, Burden, Trends, Infectious diseases, Infectious and parasitic diseases, RC109-216, Public aspects of medicine, RA1-1270 |
| More Details: | Background: Pertussis, a contagious respiratory disease, has seen a global decline in cases due to vaccination but has resurged because of waning immunity, with further impacts from the COVID-19 pandemic. This study aimed to assess the disease burden of pertussis worldwide from 1990 to 2021. Methods: Using the GBD 2021, we extracted age-standardized incidence rates (ASIR) and death rates (ASDR) of pertussis and analyzed the trends of them through calculating the estimated annual percentage change (EAPC) at global, regional and national levels from 1990 to 2021. Besides, we compared the EAPCs before and during the COVID-19 pandemic to explore the difference. Lastly, we investigated the association between age-standardized rates (ASR) and the socio-demographic index (SDI). Results: From 1990–2021, the global ASIR and ASDR of pertussis witnessed an annual decline of 2.57 % (95 %CI: 1.91–3.22 %) and 3.20 % (2.54–3.85 %) on average, respectively. During the COVID-19 pandemic, the ASR showed steep downward trends not only globally but also in diverse regions. Nevertheless, before the pandemic, Southern Sub-Sahara Africa witnessed upward trends in ASR, whose EAPCs were 0.85 % (0.67–1.02 %) for ASIR and 0.65 % (0.41–0.88 %) for ASDR. Additionally, a remarkable negative correlation was revealed between ASR and SDI (Regional level: r = -0.843; r = -0.885. National level: r = -0.621; r = -0.762. All P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1876-0341 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S1876034125000450; https://doaj.org/toc/1876-0341 |
| DOI: | 10.1016/j.jiph.2025.102696 |
| Access URL: | https://doaj.org/article/21a801df8f054908beaa7dd4702bd320 |
| Accession Number: | edsdoj.21a801df8f054908beaa7dd4702bd320 |
| Database: | Directory of Open Access Journals |
| ISSN: | 18760341 |
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| DOI: | 10.1016/j.jiph.2025.102696 |
| Published in: | Journal of Infection and Public Health |
| Language: | English |