Bibliographic Details
| Title: |
Publication and non-publication of clinical trials in PTSD: an overview |
| Authors: |
Sharain Suliman, Leigh van den Heuvel, Alexandra Suryapranata, Jonathan I. Bisson, Soraya Seedat |
| Source: |
Research Integrity and Peer Review, Vol 4, Iss 1, Pp 1-13 (2019) |
| Publisher Information: |
BMC, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:General Works |
| Subject Terms: |
Trial registry, Posttraumatic stress disorder, Publication, General Works |
| More Details: |
Abstract Background Although a large number of clinical trials on interventions demonstrating efficacy (or lack thereof) are conducted annually, much of this evidence is not accessible to scientists and clinicians. Objectives We aimed to determine the publication rate of posttraumatic stress disorder (PTSD) trials that have been registered in clinical trial registries, and the factors associated with publication. Methods Trials, completed on January 15, 2015, were identified via the US National Institutes of Health clinical trials registry, the European Union Clinical Trials Register and the WHO International Clinical Trials Registry Platform. A systematic search for publications (published by the end of March 2018) related to each of the registered trials were then performed. Results Four hundred and thirty-eight of 1982 potentially eligible trials were included. Only 34% of interventional trials were registered prior to initiation, 9% were registered within 2 months of starting and 20% after trial completion. Of the 438 included trials, 72% had generated peer-reviewed publications, while an additional 7% had disseminated results in some other form (such as on the trial database), 26 months after trial completion. Randomisation of a trial was the only factor individually associated with publication, in logistic regression analysis (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2058-8615 |
| Relation: |
http://link.springer.com/article/10.1186/s41073-019-0074-6; https://doaj.org/toc/2058-8615 |
| DOI: |
10.1186/s41073-019-0074-6 |
| Access URL: |
https://doaj.org/article/e1fd852b2be0447aae79ec419122d369 |
| Accession Number: |
edsdoj.1fd852b2be0447aae79ec419122d369 |
| Database: |
Directory of Open Access Journals |
